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This research compares the effects of one-year continuous whole egg supplement vs. egg yolk substitutes and control on anthropometry, biochemical blood parameters, metabolic enzymes and microbiome data in primary school children.
This research study determine the long-term effects of egg supplementation on growth, blood lipoproteins, blood proteins, nutritional status, metabolic enzymes and microbiomes in children, enrolling in the school lunch program.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Whole eggs (WE) | Experimental | consume 10 additional eggs per week |
|
| Egg substitute (ES) | Experimental | consume the yolk-free egg substitute equivalent to 10 eggs per week |
|
| Control group | No Intervention | Regular school meals |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| whole eggs | Dietary Supplement | whole eggs |
| |
| yolk-free egg substitutes |
| Measure | Description | Time Frame |
|---|---|---|
| changes in body weight following the dietary intervention | weight (kg), weight for age (z-score) analysis | week 0 (baseline), week 13 - 14, week 34 - 35 |
| changes in height following the dietary intervention | height (cm), height for age (z-score) analysis | week 0 (baseline), week 13 - 14, week 34 - 35 |
| change in blood protein levels following dietary intervention | transferrin (mg/dl), pre-albumin (mg/dl), albumin (g/dl) analysis | week 0 (baseline), week 13 - 14, week 34 - 35 |
| changes in blood biochemistries following dietary intervention | fasting blood sugar (mg/dl), cholesterol (mg/dl), triglyceride (mg/dl), HDL-Cholesterol (mg/dl), LDL-Cholesterol (mg/dl) | week 0 (baseline), week 13 - 14, week 34 - 35 |
| Measure | Description | Time Frame |
|---|---|---|
| changes in microbioma and stool metabolites following dietary intervention | bacterial type, fatty acids in stool | week 0 (baseline), week 13 - 14, week 34 - 35 |
| changes in blood biochemistries following dietary intervention metabolite enzyme |
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Inclusion Criteria:
1. Aged between 8-14 years
Exclusion Criteria:
4. Having contra-indication i.e. problems with blood clotting
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| Name | Affiliation | Role |
|---|---|---|
| Sophida Suta, MS. | Population Health and Nutrition Research Group, Siriraj Hospital, Mahidol University, Thailand | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine Siriraj Hospital, Mahidol University | Bangkok Noi | Bangkok | 10700 | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20420104 | Background | Mayurasakorn K, Sitphahul P, Hongto PO. Supplement of three eggs a week improves protein malnutrition in Thai children from rural areas. J Med Assoc Thai. 2010 Mar;93(3):301-9. |
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| ID | Term |
|---|---|
| D015362 | Child Nutrition Disorders |
| D044342 | Malnutrition |
| ID | Term |
|---|---|
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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A randomized controlled cluster trial
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| Dietary Supplement |
yolk-free egg substitutes |
|
lecithin-cholesterol acyltransferase (LCAT), cholesterol ester transfer protein (CETP), apolipoprotein C (APOC), apolipoprotein E (APOE)
| week 0 (baseline), week 13 - 14, week 34 - 35 |