Multimodal Assesment of Acute Cardiac Toxicity Induced by Thoracic Radiotherapy in Cancer Patients

Multimodal Assesment of Acute Cardiac Toxicity Induced by Thoracic Radiotherapy in Cancer Patients

The purpose of this study is to evaluate and compare the changes by two modalities: Imaging by Strain by Speckle Tracking and Magnetic Resonance versus soluble markers of cardiac dysfunction as early predictors of cardio-toxicity in cancer patients receiving low or high doses of radiotherapy.

Inclusion Criteria:

• ≥18 year-old patients
• With histologically confirmed thoracic cancer (breast, esophagus or lung)
• Recommendation of thoracic radiotherapy (RT) with curative intent
• With or without chemotherapy
• All patients must be able to read and understand Spanish
• All patients must sign informed consent form.

Exclusion Criteria:

• Patients with no medical records,
• Pregnant
• Previously diagnosed with severe left ventricular dysfunction or a cardiac insufficiency
• Patients with metastatic disease and indication of palliative RT
• Patients with significant comorbidities associated to a <5 year life expectancy.
• Patients previously treated with thoracic RT