The objective of the study is to evaluate the differences in the retinal microcirculation measured by OCT-Angiography in patients with type 1 diabetes between the diagnosis of the disease and after 3 months of insulin treatment.

Inclusion Criteria:

• Patients with Type 1 Diabetes at diagnosis of the disease (less than 7 days after diagnosis)
• Age equal to or greater than 18 years
• Signature of the informed consent by the patient / legal guardian.

Exclusion Criteria:

• Metabolic situation of ketosis or ketoacidosis, according to clinical criteria established in the protocol of the Endocrinology and Nutrition Service. The patient will be a candidate once the ketonemia is absent (value <1 mmol / L).
• Previous diagnosis of dyslipidemia and any previous lipid-lowering treatment
• Previous diagnosis of hypertension and any previous hypotensive treatment
• Previous diagnosis of any form of cardiovascular disease, including heart failure.
• Previous kidney disease, and presence of advanced kidney failure (estimated glomerular filtration rate <60 ml / min)
• Presence of diabetic retinopathy identifiable by conventional eye fundus or retinography, or other concomitant retinal vascular pathology (hypertensive retinopathy, venous occlusion, arterial obstruction, etc.)
• History or presence of retinal pathology that may alter its structure and / or the validity of the measurements (retinal detachment, epiretinal membrane, high myopia -understood as an axial length greater than or equal to 26mm measured by "IOL Master" biometry-, neovascular membrane, choroidal tumors, etc.)
• History of posterior uveitis or retinal vasculitis
• Glaucoma and neuro-ophthalmological pathology that can alter the neuroretinal structures.
• Refractive media opacity that prevents a correct acquisition of images and, therefore, their evaluation
• Dementia or intellectual disability that prevent proper collaboration when acquiring images

Patients diagnosed with type 1 diabetes who meet all the inclusion criteria and none of the exclusion criteria