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cyanoacrylate has an impact that may aid in the successful repair of urethra-cutaneous fistula (UCF) that occur after hypospadias surgical repair
Hypospadias is a common congenital urological birth defect. Urethro-cutaneous fistula (UCF) is the most common complication of surgical repair hypospadias and it remains the primary concern of surgeons dealing with hypospadias repair.
cyanoacrylate has been reported to enhance the healing process. this study tries to evaluate the clinical impact of cyanoacrylate on the repair of urethro-cutaneous fistula after surgical repair of hypospadias
this study evaluates the impact of using cyanoacrylate as an interposition substance in surgical repair of UCF after hypospadias in comparison to the classic surgical repair technique
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cases of group (I) cyanoacrylate glue | Experimental | Cases of group (I) underwent multilayered closure using dartos facial flap and cyanoacrylate glue as an interposition layer. |
|
| Cases of the control group (II) , classic repair | Active Comparator | Cases of the control group (II) underwent the same procedure without using cyanoacrylate. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cyanoacrylate, Isobutyl | Drug | using cyanoacrylate in the surgical repair of urethro-cutaneous fistula |
|
| Measure | Description | Time Frame |
|---|---|---|
| successful repair of the fistula | surgical outcome regarding the repair of urethro-cutaneous fistula, whether adequate healing occurred or recurrence is present | 6 months after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| postoperative complications | report of the possible postoperative complications of both groups | 6 months after surgery |
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Inclusion Criteria:
Exclusion Criteria:
Hypospadias is a male urethral congenital anomaly
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Urology department - ain shams university | Cairo | 11361 | Egypt |
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| ID | Term |
|---|---|
| D007021 | Hypospadias |
| ID | Term |
|---|---|
| D014564 | Urogenital Abnormalities |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| ID | Term |
|---|---|
| D002015 | Bucrylate |
| ID | Term |
|---|---|
| D003487 | Cyanoacrylates |
| D000179 | Acrylates |
| D000144 | Acids, Acyclic |
| D002264 | Carboxylic Acids |
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Cases of group (I) underwent multilayered closure using dartos facial flap and cyanoacrylate glue as an interposition layer.
Cases of the control group (II) underwent the same procedure without using cyanoacrylate.
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patients and their relatives were blinded to the type of the intervention
| Classic surgical repair | Procedure | classical repair of urethro-cutaneous fistula without the use of cyanoacryalte |
|
| D010409 | Penile Diseases |
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D052801 | Male Urogenital Diseases |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D009930 |
| Organic Chemicals |
| D009570 | Nitriles |
| D004659 | Enbucrilate |
| D011108 | Polymers |
| D046911 | Macromolecular Substances |
| D001697 | Biomedical and Dental Materials |
| D014014 | Tissue Adhesives |
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |