Ultra-low-dose Chest CT for HHT

Novel Ultra-low-dose Chest CT Technique to Screen for Pulmonary Arteriovenous Malformations in Pediatric Patients With Hereditary Hemorrhagic Teleangiectasia

This study aims to develop a novel ultra-low dose chest CT technology for use in Hereditary Hemorrhagic Teleangiectasia (HHT) patients and to determine the lowest possible radiation dose that is achievable without sacrificing the diagnostic quality.

Inclusion Criteria:

• Ages 1 to 17 years
• Diagnosed with positive HHT causing mutations or based on Curacao criteria

Exclusion Criteria:

• Acute respiratory distress
• Unstable cardiovascular status
• Pneumothorax, hemoptysis
• Pulmonary edema
• Pulmonary emboli
• Fractured ribs or other chest trauma
• Recent bronchoscopy
• Lung transplantation