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The investigators have developed an extremely low dose computed tomography (CT) protocol that on preliminary testing has an effective dose in the range of two chest radiographs. The investigators plan to test this exam in patients with known or suspected cancer undergoing clinically indicated chest CT.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study Group | Experimental | Patients will receive both the clinically indicated and extremely low dose exams |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Extremely Low Dose CT | Diagnostic Test | Patients undergoing a clinically indicated chest CT will also undergo the extremely low dose CT |
|
| Measure | Description | Time Frame |
|---|---|---|
| Diagnostic performance of extremely low dose CT | Sensitivity | At time of imaging |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cincinnati Children's Hospital Medical Center Burnet Campus | Cincinnati | Ohio | 45229 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39382534 | Derived | Hardie RC, Trout AT, Dillman JR, Narayanan BN, Tanimoto AA. Performance of Lung Nodule Computer-Aided Detection Systems on Standard-Dose and Low-Dose Pediatric CT Scans: An Intraindividual Comparison. AJR Am J Roentgenol. 2025 Jan;224(1):e2431972. doi: 10.2214/AJR.24.31972. Epub 2024 Oct 9. | |
| 34232694 | Derived |
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
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| Thapaliya S, Gilligan LA, Brady SL, Anton CG, Crotty EJ, Nasser MP, Geller JI, Pressey JG, Zhang B, Dillman JR, Trout AT. Comparison of 0.3-mSv CT to Standard-Dose CT for Detection of Lung Nodules in Children and Young Adults With Cancer. AJR Am J Roentgenol. 2021 Dec;217(6):1444-1451. doi: 10.2214/AJR.21.26183. Epub 2021 Jul 7. |