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Background: Transcranial direct current stimulation(tDCS) has been used to improve cognitive functions in healthy young adults.
Purpose: To investigate the effect of TDCS application on different cortex regions on cognitive function.
Methods: Sixty individuals aged 18-30 were included in the study. The participants were randomly divided into the left dorsolateral prefrontal cortex (Left DLPFC Group)(n=20), the right posterior parietal cortex (Right PPC Group)(n=20), and the sham group (Sham Group)(n=20). tDCS was applied for 20 minutes on weekdays for 2 weeks. The participants were evaluated in terms of cognitive functions with Neuropsychometric Test Battery before and after treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| LEFT DLPFC | Active Comparator | The anode electrode of tDCS was applied to the left DLPFC and the cathode electrode was connected to the contralateral shoulder. |
|
| RİGHT PPC | Active Comparator | The anode electrode of tDCS was applied to the right PPC and the cathode electrode was connected to the contralateral shoulder. |
|
| Sham | Sham Comparator | Placebo was applied by placing the electrodes in the right PPC and left DLPFC without applying current. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transcranial Direct Current Stimulation | Other | The intervention protocols were applied using tDCS (Teknofil TESsaNova). All individuals received 2 mA of anodal tDCS for 2 weeks on weekdays. All applications were done in the form of 20-minute sessions. |
| Measure | Description | Time Frame |
|---|---|---|
| Neuropsychiatric Test Battery | It is a test battery for getting detailed information about general cognitive status. | 3 weeks |
| Beck Depression Scale | It measures the symptoms seen in depression such as emotional, cognitive and motivational. It includes 21 items determine a behavioral feature related to depression. Items are numbered from 0 to 3. The goal is to objectively break down the degree of symptoms. The total score of all answers is calculated as follows: 0 to 9 points: Minimally depressive symptoms 10 to 16 points: Mild depressive symptoms Between 17 and 29 points: Moderate depressive symptoms Between 30 and 63 points: Severe depressive symptoms | 3 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Miray Budak, PhD | Medipol University | Principal Investigator |
| Lutfu Hanoglu, PhD | Medipol University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Damla Ören | Istanbul | 34000 | Turkey (Türkiye) | |||
| Medipol Mega Hospital |
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| ID | Term |
|---|---|
| D019954 | Neurobehavioral Manifestations |
| ID | Term |
|---|---|
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D065908 | Transcranial Direct Current Stimulation |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D003295 | Convulsive Therapy |
| D013000 | Psychiatric Somatic Therapies |
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| Istanbul |
| 34000 |
| Turkey (Türkiye) |
| D004191 | Behavioral Disciplines and Activities |
| D004597 | Electroshock |
| D011580 | Psychological Techniques |