This is a single arm pilot study of a new smartphone app to support adherence to PrEP medication for HIV prevention in public clinics in Virginia.

Testing the impact of a smart phone application's impact on PrEP uptake and adherence.

The app features daily medication reminders, daily mood and stress evaluations, a community message board for social support, and patient-provider secure, HIPAA compliant private messaging between patients and clinic providers. Participants will be recruited from VDH clinics. We will evaluate the adherence and uptake rates of PrEP among study participants. Usage data will be collected from the application, and from participant surveys at 30 day, 3 month, and 6 month study timepoints. Surveys will include questionnaires on medication adherence, empathy of providers, experiences with the app, stigma and disclosure attitudes, and social support, along with mental health screening. The study will be analyzed as a prospective one arm study by comparing baseline to 3M and 6M surveys, along with examining and characterizing app usage across time.

Inclusion Criteria:

• 18 years of age or older
• one or considering being on PrEP for HIV prevention
• Patient at a VDH or VDH funded clinic
• ability to read at a 5th grade reading level

Exclusion Criteria:

• HIV positive individuals
• Persons under the age of 18