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The transradial access (TRA) is currently the preferred approach for percutaneous coronary intervention (PCI). However, in patients with ACUTE ST-segment elevation myocardial infarction (STEMI) after emergency PCI, the high incidence of THE radial artery RAO limits the future choice of the radial artery for percutaneous intervention. The literature reported that distal transradial access (dTRA) significantly reduced RAO after elective PCI, but the application of dTRA in emergency PCI in STEMI has not been reported. We have completed 126 cases of dTRA undergoing emergency PCI after STEMI, which has been preliminarily confirmed to be safe and effective. A single-center, open, prospective, randomized controlled study is planned to compare the use of dTRA and TRA in emergency PCI in STEMI patients. The primary endpoint was the INCIDENCE of RAO within 24 hours after surgery. This clinical study verified that dTRA compared with TRA could reduce the RAO incidence of STEMI patients after emergency PCI. The project will explore a new artery approach to reduce RAO, and provide a basis for the selection of artery approach in STEMI emergency PCI patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Distal transradial access (dTRA) | Experimental | Distal transradial access for primary percutaneous coronary intervention in STEMI patients |
|
| Transradial access (TRA) | Active Comparator | Transradial access for primary percutaneous coronary intervention in STEMI patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Arterial access | Procedure | Arterial access for primary percutaneous coronary intervention in STEMI patients |
|
| Measure | Description | Time Frame |
|---|---|---|
| The RAO incidence during hospitalization | The incidence of radial artery occlusion during hospitalization | 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Puncture time | Puncture time | During the intervention |
| Compression time | Compression time | 4-24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xin Sun, MD | Contact | +86-755-22942705 | sunxinflying@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Shaohong Dong, MD | Shenzhen People's Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shenzhen People's Hospital | Recruiting | Shenzhen | Guangdong | 518020 | China |
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| ID | Term |
|---|---|
| D000072657 | ST Elevation Myocardial Infarction |
| D001157 | Arterial Occlusive Diseases |
| ID | Term |
|---|---|
| D009203 | Myocardial Infarction |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D062666 | Vascular Access Devices |
| ID | Term |
|---|---|
| D057785 | Catheters |
| D004864 | Equipment and Supplies |
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| Puncture success rate | Puncture success rate | During the intervention |
| Incidence of hematoma, finger numbness or pain during hospitalization | Incidence of hematoma, finger numbness or pain during hospitalization | 7days |
| Incidence of RAO at 1 and 6 months after surgery | Incidence of RAO at 1 and 6 months after surgery | 1 and 6 months |
| D014652 |
| Vascular Diseases |
| D007238 | Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |