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The site of arterial access for coronary angiography and intervention has been the focus of research for decades as it is the source of major complications. Transradial access (TRA) reduces complications among patients undergoing percutaneous coronary procedures but is reported with the complication of radial artery occlusion (RAO) that limits the radial artery for future needs.
Distal radial access (dTRA) has recently gained global popularity as an alternative access route for vascular procedures. Among the benefits of dTRA are the low risk of entry site bleeding complications, the low rate of radial artery occlusion, and improved patient and operator comfort.
This study aims to reveal the feasibility and safety of dTRA and routine TRA procedures in acute coronary syndrome patients. The primary endpoints are forearm radical occlusion rate and major adverse cardiovascular events (MACEs) in the two groups, respectively. Investigators will also focus on puncture success in diagnostic and interventional cases, rate of One attempt success, access time, procedure time, crossover rate, contrast dose of patients, fluoroscopy time and dose, and healthcare cost of each group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| dTRA group | Experimental | Investigators perform percutaneous coronary intervention by dTRA |
|
| TRA group | Other | Investigators perform percutaneous coronary intervention by conventional TRA |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| distal TRA group | Procedure | dTRA for PCI procedure to ACS patients. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Forearm radical occlusion | Doppler ultrasound to determine whether patients suffer forearm radial occlusion | during procedure |
| MACEs | Major Adverse Cardiovascular Events, including cardiovascular death, myocardial infarction and heart failure. | during procedure |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of One attempt success | Rate of One attempt success of 2 kinds of procedure | during procedure |
| Access time | Access time of 2 kinds of procedure |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shenzhen People's hospital | Shenzhen | Guangdong | 518000 | China |
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| ID | Term |
|---|---|
| D054058 | Acute Coronary Syndrome |
| D001157 | Arterial Occlusive Diseases |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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| conventional TRA group |
| Procedure |
Conventional TRA for PCI procedure to ACS patients |
|
| during procedure |
| Procedure time | Procedure time of 2 kinds of procedure | during procedure |
| Crossover rate | Crossover rate of 2 kinds of procedure | during procedure |
| Contrast dose | Contrast dose of 2 kinds of procedure | during procedure |
| Fluoroscopy dose | Fluoroscopy dose of 2 kinds of procedure | during procedure |
| hand hematoma | hand hematoma rate of 2 kinds of procedure | during procedure |
| The total cost in hospitalization | Healthcare cost . | up to 2 years |