Selective exercise programs specific to muscle groups, with the workload to be done in line with the muscle's own structure, can enable more strength to be released with less fatigue in MS, and this increase in strength can increase balance and functional activities. to determine the effects of type training (selective exercise training), eccentric and concentric training on function, balance, fatigue and muscle architecture.

Recovery and enhancement of muscle function in MS is one of the main goals in physiotherapy and rehabilitation. In literature studies, it is stated that eccentric and concentric exercises are effective exercise approaches in increasing strength and reducing fatigue. However, the best exercise method is not yet clear in terms of providing better performance adaptation with less fatigue. Considering the architectural features of the lower extremity muscles, it is aimed to increase the angle of pennation with programs that include concentric strengthening of the quadriceps, gastro-soleus and gastrocnemius muscles, which are suitable muscle groups to produce large forces by design. With programs that include eccentric strengthening of the hamstring and tibialis anterior muscles that function in a wide range of motion and have high excursion ability, it is aimed to increase fiber length.

Inclusion Criteria:

• Between the ages of 18-50,
• With an Extended Disability Status Scale (EDSS) score of 4 or less,
• No regular exercise habit
• Able to walk on the treadmill,
• No pregnancy,
• Not receiving corticosteroid treatment in the last month,
• Fampridine etc. in the last 1 month. not taking medication,
• Patients who have not received Botox treatment in the last 6 months

Exclusion Criteria:

patients who do not agree to volunteer