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This subject is mainly to study difference of Congenital cataract preoperative related parameters in children with or without Microcornea within Less than one year old. A total of 186 eyes of 117 people were collected with relevant ocular biological parameters, including age, horizontal diameter of the cornea, Eye axis, intraocular pressure, steep axis of corneal curvature, flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth. At present, because the definition of patients with small cornea is not clear enough, the study subjects are divided into 4 groups according to the horizontal corneal diameter of 9.0mm, 9.5mm, and 10.0mm, namely ≤9.0mm group, 9~9.5mm group, 9.5~10.0mm group and The >10.0mm group compares the differences between each other, and tries to provide a reference for the diagnosis of children with small cornea at a young age.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Corneal horizontal diameter ≤9.00mm group |
| ||
| Corneal horizontal diameter 9.00mm~9.50mm group |
| ||
| Corneal horizontal diameter 9.50mm~10.00mm group |
| ||
| Corneal horizontal diameter >10.00mm group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Collect ocular biological parameters including age, corneal diameter, eye axis, intraocular pressure, steep&flat axis of corneal curvature, corneal thickness, lens thickness, anterior chamber depth | Device | observation |
| Measure | Description | Time Frame |
|---|---|---|
| horizontal diameter of the cornea | Use a ruler to measure during surgery | 2015.5.1-2020.12.1 |
| Measure | Description | Time Frame |
|---|---|---|
| age | 2015.5.1-2020.12.1 | |
| Eye axis | A-type ultrasonic measuring instrument | 2015.5.1-2020.12.1 |
| intraocular pressure |
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Inclusion Criteria:
Exclusion Criteria:
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From May 2015 to December 2020,Congenital cataract children with or without Microcornea within one year of age attending the Eye Optometry Hospital of Wenzhou Medical University
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Wenzhou Medical University | Hangzhou | Zhejiang | 313000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30498267 | Background | Zhang H, Chen Z, He K, Chang P, Zhao Y, Huang X, Li J, Jin Z, Zhao YE. Unique presentation of congenital cataract concurrent with microcornea, microphthalmia plus posterior capsule defect in monozygotic twins caused by a novel GJA8 mutation. Eye (Lond). 2019 Apr;33(4):686-689. doi: 10.1038/s41433-018-0277-y. Epub 2018 Nov 29. No abstract available. | |
| 28991349 |
| Label | URL |
|---|---|
| Evaluation of the safety of sclerotomy incision in patients with choroidal colobomas with/without associated microcornea | View source |
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i care handheld tonometer |
| 2015.5.1-2020.12.1 |
| steep axis of corneal curvature | Handheld eye curvature measuring instrument | 2015.5.1-2020.12.1 |
| flat axis of corneal curvature | Handheld eye curvature measuring instrument | 2015.5.1-2020.12.1 |
| corneal thickness | Handheld corneal thickness measuring instrument | 2015.5.1-2020.12.1 |
| lens thickness | A-type ultrasonic measuring instrument | 2015.5.1-2020.12.1 |
| anterior chamber depth | SS-OCT | 2015.5.1-2020.12.1 |
| Matalia J, Shirke S, Shetty KB, Matalia H. Surgical Outcome of Congenital Cataract in Eyes With Microcornea. J Pediatr Ophthalmol Strabismus. 2018 Jan 1;55(1):30-36. doi: 10.3928/01913913-20170703-13. Epub 2017 Oct 9. |
| 25011027 | Background | Liu T, Zhang M, Xu B, Wang W, Lee J, Gao Y, Zhang X. Evaluation of the safety of sclerotomy incision in patients with choroidal colobomas with/without associated microcornea. Retina. 2014 Nov;34(11):2300-5. doi: 10.1097/IAE.0000000000000227. |
| Surgical Outcome of Congenital Cataract in Eyes With Microcornea. J Pediatr Ophthalmol Strabismus. | View source |
| Unique presentation of congenital cataract concurrent with microcornea, microphthalmia plus posterior capsule defect in monozygotic twins caused by a novel GJA8 mutation. | View source |
| ID | Term |
|---|---|
| D014065 | Tonometry, Ocular |
| ID | Term |
|---|---|
| D003941 | Diagnostic Techniques, Ophthalmological |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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