Idiopathic purpura fulminans by anti-protein S antibody is a very rare but potentially extremely serious entity. The data in the literature are poor with only isolated report boxes and a single series of less than 10 boxes. The creation of a larger series of cases would make it possible to better understand this pathology and to offer assistance in diagnosis and management.

Inclusion criteria:

• diagnostic of idiopathic purpura fulminans
• Acquired protein S deficiency

Exclusion criteria:

- Other infecious purpura diagnosis

Children with diagnostic of idiopathic purpura fulminans and acquired protein S deficiency

NC