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The incidence in pediatrics is very low (about 0.5 per million according to a French study) and therefore the data on the pathology very poor, especially on the therapeutic level.
Without appropriate treatment, the mortality rate of the pathology is very high.
Existing treatments are almost exclusively composed of immunomodulatory and/or immunosuppressive treatments.
Complications related to pathology and iatrogeny are among the first causes of mortality from this pathology and deserve to be studied in order to be known and if possible avoided. The purpose of the study is to achieve a national comparison of clinical and therapeutic practices.
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| Measure | Description | Time Frame |
|---|---|---|
| Retrospective study of clinical and therapeutic practices at the national level. | Files analysed retrospectively from January 01, 2011 to December 31, 2020 will be examined] |
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Inclusion criteria:
Exclusion criteria:
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Minor subject (<18 years old) with diagnosis of ANCA vasculitis according to the international criteria for defining the pathology, GPA or MPA form between 2011 and 2020.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ariane ZALOSZYC, MD | Contact | 33 3 88 12 77 49 | ariane.zaloszyc@chru-strasbourg.fr | |
| Saïd CHAYER, PhD, HDR | Contact | said.chayer@chru-strasbourg.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Pédiatrie 1 - CHU de Strasbourg - France | Recruiting | Strasbourg | 67091 | France |
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| ID | Term |
|---|---|
| D056648 | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis |
| D014657 | Vasculitis |
| ID | Term |
|---|---|
| D056647 | Systemic Vasculitis |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D017445 | Skin Diseases, Vascular |
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| D012871 |
| Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |