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Late sequelae of a cesarean section related to a uterine scar defects include gynecological symptoms and obstetric complications. The aim of this study was to evaluate the incidence and characteristics of cesarean scar defects after uterine closure by double-layer barbed suture.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Low transverse hysterotomy closed by double-layer unidirectional barbed suture | Patients who had undergone cesarean section during which the low transverse hysterotomy was closed by double-layer unidirectional barbed suture |
| |
| Low transverse hysterotomy closed by conventional double-layer smooth suture | Patients who had undergone cesarean section during which the low transverse hysterotomy was closed by conventional double-layer smooth suture |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Clinical and ultrasonographic assessment | Procedure | Routinely assessment by objective examination and transvaginal ultrasonographic scan 6, 12, and 24 months after the surgical procedures |
| Measure | Description | Time Frame |
|---|---|---|
| Number of uterine scar defects | Number of simple and complex uterine scar defects is evaluated by transvaginal ultrasound | 6 months after the cesarean section |
| Number of uterine scar defects | Number of simple and complex uterine scar defects is evaluated by transvaginal ultrasound | 12 months after the cesarean section |
| Number of uterine scar defects | Number of simple and complex uterine scar defects is evaluated by transvaginal ultrasound | 24 months after the cesarean section |
| Measure | Description | Time Frame |
|---|---|---|
| Residual myometrium thickness (RMT), depth, width and length of uterine scar defects | RMT, depth, width, and length are evaluated by transvaginal ultrasound | 6 months after the cesarean section |
| Residual myometrium thickness (RMT), depth, width and length of uterine scar defects |
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Inclusion Criteria:
- Patients who underwent elective cesarean section at ≥ 37 weeks of gestation
Exclusion Criteria:
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Patients who underwent elective cesarean section at ≥37 weeks of gestation
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| Name | Affiliation | Role |
|---|---|---|
| Fabio Barra, MD | IRCCS Ospedale Policlinico San Martino | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| IRCCS Ospedale Policlinico San Martino | Genoa | 16132 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33404082 | Background | Agarwal S, D'Souza R, Ryu M, Maxwell C. Barbed vs conventional suture at cesarean delivery: A systematic review and meta-analysis. Acta Obstet Gynecol Scand. 2021 Jun;100(6):1010-1018. doi: 10.1111/aogs.14080. Epub 2021 Feb 5. | |
| 34146146 | Background | Alessandri F, Evangelisti G, Centurioni MG, Gustavino C, Ferrero S, Barra F. Fishbone double-layer barbed suture in cesarean section: a help in preventing long-term obstetric sequelae? Arch Gynecol Obstet. 2021 Sep;304(3):573-576. doi: 10.1007/s00404-021-06121-8. |
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RMT, depth, width, and length are evaluated by transvaginal ultrasound |
| 12 months after the cesarean section |
| Residual myometrium thickness (RMT), depth, width and length of uterine scar defects | RMT, depth, width, and length are evaluated by transvaginal ultrasound | 24 months after the cesarean section |
| Number of patients with postmenstrual spotting | Number of patients with postmenstrual spotting is evaluated by medical interview | 6 months after the cesarean section |
| Number of patients with postmenstrual spotting | Number of patients with postmenstrual spotting is evaluated by medical interview | 12 months after the cesarean section |
| Number of patients with postmenstrual spotting | Number of patients with postmenstrual spotting is evaluated by medical interview | 24 months after the cesarean section |
| Number of patients with dysmenorrhea | Number of patients with dysmenorrhea is evaluated by medical interview with VAS (visual analogue scale) | 6 months after the cesarean section |
| Number of patients with dysmenorrhea | Number of patients with dysmenorrhea is evaluated by medical interview with VAS (visual analogue scale) | 12 months after the cesarean section |
| Number of patients with dysmenorrhea | Number of patients with dysmenorrhea is evaluated by medical interview with VAS (visual analogue scale) | 24 months after the cesarean section |
| 29536581 | Background | Jordans IPM, de Leeuw RA, Stegwee SI, Amso NN, Barri-Soldevila PN, van den Bosch T, Bourne T, Brolmann HAM, Donnez O, Dueholm M, Hehenkamp WJK, Jastrow N, Jurkovic D, Mashiach R, Naji O, Streuli I, Timmerman D, van der Voet LF, Huirne JAF. Sonographic examination of uterine niche in non-pregnant women: a modified Delphi procedure. Ultrasound Obstet Gynecol. 2019 Jan;53(1):107-115. doi: 10.1002/uog.19049. |