Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
To evaluate the effect of platelet-rich plasma (PRP) injection on pain, function and quality of life in patients with hip osteoarthritis.
After being informed about the study and potential risk, all patients giving written informed consent will undergo study entry.
Each patient received three times intra-articuler injections of PRP under ultrasound guidance, and they were administered once a week.
Baseline: Visual Analog Scale (VAS) including movement, rest and night, the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and SF-36 assessment
1st month: VAS, WOMAC and SF-36 assessment
3rd month: VAS, WOMAC and SF-36 assessment
6th month: VAS, WOMAC and SF-36 assessment
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PRP injection group | Other | Intra-articular PRP injection with ultrasound guidance Three times PRP injections with an interval of one week |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| intra-articular PRP injection | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change from baseline Visual Analog Scale (VAS) score at 1-month, 3-month and 6-month | The VAS is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between 'no pain' and 'worst pain'. | Baseline, 1st month, 3rd month, 6th month |
| Change from baseline Western Ontario and McMaster University Osteoarthritis Index (WOMAC) score at 1-month, 3-month and 6-month | The scores for each subscale are summed up, with a possible score range of 0-20 for Pain, 0-8 for Stiffness, and 0-68 for Physical Function. Usually a sum of the scores for all three subscales gives a total WOMAC score, however there are other methods that have been used to combine scores. Higher scores: worse pain, stiffness, and functional limitations. | Baseline, 1st month, 3rd month, 6th month |
| Change from baseline SF-36 score at 1-month, 3-month and 6-month | The SF-36 is a 36-item self-report measure of health-related quality of life. It has eight subscales measuring different domains of health-related quality of life: physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health . Two component scores are derived from the eight subscales: a physical health component score and a mental health component score. High scores: good quality of life | Baseline, 1st month, 3rd month, 6th month |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Jülide Öncü Alptekin | Şişli Hamidiye Etfal Training and Research Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Şişli Hamidiye Etfal Training and Research Hospital | Istanbul | Şişli | 34371 | Turkey (Türkiye) |
Not provided
| ID | Term |
|---|---|
| D015207 | Osteoarthritis, Hip |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
Not provided
Not provided
The patients with mono-lateral hip pain , grade 1 or 2 hip osteoarthritis according to the Kellgren-Lawrence classification
Not provided
Not provided
Not provided
Not provided
| D012216 |
| Rheumatic Diseases |