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This is a prospective, multicenter, self-control clinical trial designed to assess the efficacy of AccuFFRangio, a novel method for evaluating the functional significance of coronary stenosis from coronary angiography, with FFR as the reference standard.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| FFR | Diagnostic Test | FFR measured by pressure wire, AccuFFRangio computed by coronary angiographic images |
|
| Measure | Description | Time Frame |
|---|---|---|
| Diagnostic accuracy of AccuFFRangio to determine hemodynamically significant coronary artery stenosis compared to FFR as the reference standard | Hemodynamically significant coronary artery stenosis: FFR≤0.8 | 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Sensitivity and specificity of AccuFFRangio to determine hemodynamically significant coronary artery stenosis compared to FFR as the reference standard | Hemodynamically significant coronary artery stenosis: FFR≤0.8 | 7 days |
| AUC of AccuFFRangio for discrimination of hemodynamically significant coronary artery stenosis |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with stable angina, unstable angina or myocardial infarction after the acute phase
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Second Affiliated Hospital, Zhejiang University School of Medicine | Hanzhou | Zhejiang | 310009 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39719423 | Derived | Jiang J, Hu Y, Li C, Dong L, Xu J, Tang L, Jiang W, Du C, Jiang X, Lyu Y, Leng X, Li C, Koo BK, Xiang J, Ge J, Wang J. Diagnostic Accuracy of Computational Fluid Dynamics-Based Fractional Flow Reserve Derived From Coronary Angiography: The ACCURATE Study. J Am Heart Assoc. 2025 Jan 7;14(1):e035672. doi: 10.1161/JAHA.124.035672. Epub 2024 Dec 24. |
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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Hemodynamically significant coronary artery stenosis: FFR≤0.8 |
| 7 days |
| D001161 |
| Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |