Angiogram Based Fractional Flow Reserve FFRangio - A Validation Study

Angiogram Based Fractional Flow Reserve FFRangio - A Validation Study

In the present study we aim at validating the computation of FFRangio values from the angiogram by comparing them to measured wire-based FFR values, in a larger scale and in a completely blinded manner. Investigation of a wide range of users in various conditions may strengthen the reliability of the FFRAngio measurements.

Inclusion Criteria:

• Male and female above 18 years old age which undergo FFR as part of their standard care
• TIMI Grade Flow is equal to 3
• LVEF larger than 45%.
• Subjects with multi-vessel coronary artery disease, with NSTEMI are allowed.

Exclusion Criteria:

• Contraindicated for FFR examination or adenosine administration
• STEMI
• CTO
• TIMI Grade Flow below 3
• Arteries supplying akinetic or severe hypokinetic territories
• Prior CABG on the study vessel
• Left Main stenosis, In-stent restenosis and Collaterals
• Diffused atherosclerosis diseases and tandem lesions
• Aorto-ostial lesion