In the present study we aim at validating the computation of FFRangio values from the angiogram by comparing them to measured wire-based FFR values, in a larger scale and in a completely blinded manner. Investigation of a wide range of users in various conditions may strengthen the reliability of the FFRAngio measurements.

Inclusion Criteria:

• Male and female above 18 years old age which undergo FFR as part of their standard care
• TIMI Grade Flow is equal to 3
• LVEF larger than 45%.
• Subjects with multi-vessel coronary artery disease, with NSTEMI are allowed.

Exclusion Criteria:

• Contraindicated for FFR examination or adenosine administration
• STEMI
• CTO
• TIMI Grade Flow below 3
• Arteries supplying akinetic or severe hypokinetic territories
• Prior CABG on the study vessel
• Left Main stenosis, In-stent restenosis and Collaterals
• Diffused atherosclerosis diseases and tandem lesions
• Aorto-ostial lesion

This study will enroll male and female subjects above the age of 18, with stable angina who were referred to coronary angiography and have an FFR measurement in at least one coronary artery.