Evaluation of the Effect of Narrowband UVB Versus Methotrexate on Serum TWEAK Level in Psoriasis

Evaluation of the Effect of Narrowband Ultraviolet B Versus Methotrexate on Serum TWEAK Level in Psoriasis

The aim of the study is to evaluate the effect of NB-UVB versus MTX on serum TWEAK level in psoriatic patients.

Inclusion Criteria:

• Patients with moderate to severe plaque psoriasis of any age and gender.

Exclusion Criteria:

• History of psoriasis treatment with systemic and biological agents prior to the study for at least 3 months.
• Pregnancy and lactation.
• Infections
• Patients with chronic diseases: hepatic disorders, hematologic disease, chronic renal failure or cancer