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Immediate implant placement into fresh extraction sockets is gaining popularity because of fewer clinical procedures and maintenance of bone architecture compared to conventional methods, thus reducing the treatment time and increasing patient satisfaction. In addition, the survival rate of the immediate implantation is comparable to that of the healed implantation sites. Recently, ATBG made from compromised teeth was applied in bone defects and resulted in a good clinical efficacy. Moreover, it is more accepted by patients to use extracted teeth as a bone graft material, especially in the case of immediate implant placement. In 2020, KizildaÄŸ and coworkers studied the outcome of PRF as an adjunct with ATBG on bone healing in rabbit peri-implant osseous defects. They reported that combination of ATBG with PRF contributed to significantly higher new bone formation and better bone/implant contact in rabbits with peri-implant bone defects. The main hypothesis behind this study is that using L-PRF with ATBG following immediate implant placement could promote stabilization of graft particles and enhance new bone formation with a shorter time. Therefore, the purpose of this study was to compare the clinical and radiographic outcomes of ATBG on bone formation with or without L-PRF around immediately placed dental implants in periodontally compromised teeth.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| L-PRF with ATBG around implant | Experimental | L-PRF clots to cover ATBG around immediately placed dental implants in the extraction sockets |
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| ATBG around implant | Active Comparator | ATBG around immediately placed dental implants in the extraction sockets |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| immediate implant placement with ATBG and L-PRF | Combination Product | immediate implant placement using ATBG as a graft material, with L-PRF |
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| Measure | Description | Time Frame |
|---|---|---|
| clinical evaluation of bone formation around immediately placed dental implants | Changes on bone formation using ATBG with or without L-PRF around immediately placed dental implants in periodontally compromised teeth | 9 months |
| radiographic outcome around immediately placed dental implants | the radiographic outcome of ATBG on bone formation with or without L-PRF around immediately placed dental implants in periodontally compromised teeth | 9 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Dalia R Issa, PhD | Kafrelsheikh University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dentistry, Kafrelsheikh University | Kafr ash Shaykh | 33511 | Egypt |
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| immediate implant placement with ATBG | Combination Product | immediate implant placement using ATBG as a graft material without L-PRF |
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