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This observational real-world study is designed to evaluate the efficacy and safety of camrelizumab for the treatment of Chinese NSCLC patients.
Camrelizumab is a humanized antibody for cancer immunotherapy. The National Medical Products Administration (NMPA, China) approved camrelizumab as a first-line treatment of certain patients with NSCLC. This is a multicenter non-interventional study, NSCLC patients who have been treated with camrelizumab will be included. The main objective of this study is to evaluate the efficacy and safety of camrelizumab in the clinical practice.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Camrelizumab | Drug | Camrelizumab-treated advanced NSCLC Patients with advanced non-small cell lung cancer treated with camrelizumab. Dosage form, dosage, frequency and duration of camrelizumab is determined according to the investigator's actual clinical practice. |
|
| Measure | Description | Time Frame |
|---|---|---|
| AE,Grade 3-5 | Safety of the general population:Serious Adverse Events (AE),Grade 3-5. | From April 1, 2021 to Septeember 30, 2024 |
| Measure | Description | Time Frame |
|---|---|---|
| pCR | Neoadjuvant therapy population: pathological complete response rate (pCR). | From April 1, 2021 to December 30, 2024 |
| MPR | Neoadjuvant population: main pathological response rate (MPR) |
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Inclusion Criteria:
Exclusion Criteria:
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Total 1000 patients who should accept camrelizumab with NSCLC will be enrolled. The patients should be registered consecutively in each site.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Chongrui Xu, Doctor | Contact | +8618696164925 | xucr001@gmail.com | |
| Yilong Wu, Doctor | Contact | +86 020 83827812 | 51221 | syylwu@live.cn |
| Name | Affiliation | Role |
|---|---|---|
| Yilong Wu | Guangdong Lung Cancer Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences | Principal Investigator |
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| ID | Term |
|---|---|
| D002289 | Carcinoma, Non-Small-Cell Lung |
| ID | Term |
|---|---|
| D002283 | Carcinoma, Bronchogenic |
| D001984 | Bronchial Neoplasms |
| D008175 | Lung Neoplasms |
| D012142 | Respiratory Tract Neoplasms |
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| ID | Term |
|---|---|
| C000631724 | camrelizumab |
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| From April 1, 2021 to December 30, 2024 |
| R0 resection rate | Neoadjuvant therapy population: R0 resection rate. | From April 1, 2021 to December 30, 2022 |
| ORR | Advanced non-small cell lung cancer: objective response rate (ORR). | From April 1, 2021 to December 30, 2022 |
| PFS | Advanced non-small cell lung cancer: progression-free survival. | From April 1, 2021 to December 30, 2022 |
| OS | Advanced non-small cell lung cancer: Overall survival. | From April 1, 2021 to December 30, 2022 |
| D013899 |
| Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |