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The study aimed to investigate the effect of applying cognitively challenging exergames using fully immersive virtual reality in patients with Parkinson's disease.
It has been reported that dual-task training involving both cognitive and physical functions helps improve walking speed during dual-task performance without increasing the fall risk in patients with Parkinson's disease (PD). Compared with conventional physical therapy, there are studies that dual-task training significantly improved walking speed and stride in PD patients. In addition, a systematic review study has been reported that it helps to improve balance and cognitive function when dual-task training is performed for patients with neurological diseases including Parkinson's disease.
Virtual reality is expected to promote functional recovery in patients with neurological disorders in terms of providing an enriched environment, goal-directed tasks and repetition, and inducing interest and motivation. Therefore, the study aimed to investigate the effect of applying cognitively challenging exergames using fully immersive virtual reality in patients with PD.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Virtual reality exergames | Experimental | Cognitively challenging exergames using fully immersive virtual reality with a head-mounted display (HTC Vive; HTC Co., New Taipei City, Taiwan) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Virtual reality exergames | Device | A total of 10 sessions were held for 30 minutes, 2 to 3 times a week for exergames using fully immersive virtual reality under the assistance of an occupational therapist. |
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive dual-task interference (%) in Timed-up & go test | at study completion, an average of 1 month | |
| Physical dual-task interference (%) in Timed-up & go test | at study completion, an average of 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Timed-up & go test (sec): single task | at study completion, an average of 1 month | |
| Timed-up & go test (sec): cognitive dual-task | at study completion, an average of 1 month | |
| Measure | Description | Time Frame |
|---|---|---|
| Simulator sickness questionnaire (SSQ) | at 1st session (an average of 3 days) and at study completion (an average of 1 month) |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Han Gil Seo, MD, PhD | Seoul National University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Seoul | 03080 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37464349 | Derived | Yun SJ, Hyun SE, Oh BM, Seo HG. Fully immersive virtual reality exergames with dual-task components for patients with Parkinson's disease: a feasibility study. J Neuroeng Rehabil. 2023 Jul 18;20(1):92. doi: 10.1186/s12984-023-01215-7. |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| Timed-up & go test (sec): physical dual-task |
| at study completion, an average of 1 month |
| The Unified Parkinson's Disease Rating Scale | The higher the score, the more negative the result | at study completion, an average of 1 month |
| Berg balance scale | The higher the score, the more positive the result | at study completion, an average of 1 month |
| Stroop test | at study completion, an average of 1 month |
| Trail making test | at study completion, an average of 1 month |
| Digit span test | at study completion, an average of 1 month |
| New Freezing of Gait Questionnaire (NFOGQ) | at study completion, an average of 1 month |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |