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The analysis of portal vein blood flow is important when assessing the severity and progression of liver disease. It is important to understand normal liver regulation in order to appreciate the evaluation of the effect of treatment during the disease progression. The influence of respiration on hepatic hemodynamics is still poorly understood, although some studies have shown a significant impact. The purpose of this project is to quantify the blood flow variations in the portal vein at different positions during the respiratory cycle by using a fast MRI sequence and an Echo Planar (EPI) acquisition.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| peripheral ECG | Other | Subjects will be placed in supine position. The systematic use of a headset will reduce the noise inherent to the machine. A cardiac synchronization system using peripheral ECG allows the synchronization with the subject's heart rate. | ||
| Standard MRI | Other | Standard MRI examination using a torso coil consists of morphological and phase-contrast flow sequences(standard and EPI acquisitions). |
| Measure | Description | Time Frame |
|---|---|---|
| flow rates variation between the fast sequence averaged values and the standard sequence | flow rates variation between the fast sequence averaged values and the standard sequence during free breathing. | 30 minutes |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Amiens | Amiens | 80480 | France |
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