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Prospective research in which patients who applied to UUTF Gynecology and Obstetrics ART center for the treatment of infertility (inability to conceive despite one year of unprotected sexual intercourse), who will undergo IVF due to PCOS and unexplained infertility
As of 01/10/2020, IVF cycles of patients with PCOS (n = 105) and unexplained infertility (n = 105) who have applied to Bursa Uludag University Gynecology and Obstetrics Department, Reproductive Treatments Center, will be included in the study. Demographic data of all patients (age, BMI, smoking), presence of hyperandrogenism findings such as systemic diseases, hirsutism, alopecia, FSH, LH, LH/FSH ratio, estradiol levels, pregestational serum AMH levels, uterine anomalies detected by transvaginal USG or hysterosalpingography, controlled ovarian hyperstimulation protocols and doses; Besides, DHEA-S, Free Testosterone, 17-OH Progesterone levels will be recorded in patients diagnosed with PCOS. All these data are routine laboratory and imaging parameters of patients who underwent in vitro fertilization in our UYTE center. Pregnancy results of the patients (biochemical pregnancy, anembryonic pregnancy, abortion, clinical pregnancy, live birth), perinatal results and complications during clinical pregnancy, delivery ways, and newborn APGAR scores will be recorded. Results will be compared with patients in the control group diagnosed with unexplained infertility.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study Group | Infertile patients due to polycystic ovarian syndrome |
| |
| Control Group | Infertile patients due to unexplained infertility |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ultrasound and Hysterosalpingography | Diagnostic Test | Ultrasound and Hysterosalpingography |
|
| Measure | Description | Time Frame |
|---|---|---|
| The rate of Mullerian Abnormality | ESHRE&ESGE uterine abnormality classification | One year |
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Inclusion Criteria:
Exclusion Criteria:
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Infertile Patients who undergo IVF&ICSI treatment
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Gürkan Uncu, Prof. | Contact | +902242952541 | guncu@gurkanuncu.org | |
| Kiper Aslan, M.D. | Contact | +902242952541 | kiperaslan@yahoo.com.tr |
| Name | Affiliation | Role |
|---|---|---|
| Özge Albayrak, M.D | Bursa Uludag University School of Medicine ART Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Uludag University ART Center | Recruiting | Bursa | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D020345 | Enterocolitis, Necrotizing |
| D011085 | Polycystic Ovary Syndrome |
| ID | Term |
|---|---|
| D004760 | Enterocolitis |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| ID | Term |
|---|---|
| D014463 | Ultrasonography |
| D007047 | Hysterosalpingography |
| ID | Term |
|---|---|
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D011859 | Radiography |
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| D007410 |
| Intestinal Diseases |
| D010048 | Ovarian Cysts |
| D003560 | Cysts |
| D009369 | Neoplasms |
| D010049 | Ovarian Diseases |
| D000291 | Adnexal Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D000091662 | Genital Diseases |
| D006058 | Gonadal Disorders |
| D004700 | Endocrine System Diseases |
| D003944 |
| Diagnostic Techniques, Obstetrical and Gynecological |