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Patients having juvenile idiopathic arthritis (according to ILAR criteria) with hip arthritis were divided into 3 groups. Group 1 received hip denervation and group 2 controlled and received a subcutaneous injection of saline, and group 3 received intra-articular triamcinolone. Outcome measures included pain, tenderness, range of motion, SOLAR, HARISS score. These outcomes were measured at baseline, 2 weeks, and 16 weeks
The aim of the study is to test the effect of denervation of the active hip in JIA and compare it with a placebo without changing systemic treatment during the study. Outcome measures included pain, range of motion, SOLAR score, and Harris functional score.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hip denervation group | Active Comparator | This group will receive Lidocaine 2% block of the femoral and obturator genicular branches. |
|
| control group | Placebo Comparator | this group will receive saline injection subcutaneously at the same places. |
|
| Steroid | Active Comparator | This group with receiving an intra-articular injection of 80mg triamcinolone |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lidocaine | Drug | denervation of the obturator and femoral genicular branches by Lidocaine 2 % |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in visual analogue scale | a scale from 0-100 will be used 0 means no pain 100 means the maximum pain | Baseline, 2 weeks and 16 weeks |
| Change in range of motion | flexion, internal rotation, external rotation range will be calculated | Baseline, 2 weeks and 16 weeks |
| Change in Harris functional score | 100 means best results and 0 means worst results | Baseline, 2 weeks and 16 weeks |
| semiquantitative tenderness score | 0 means no tenderness and 3 means maximum tenderness | Baseline, 2 weeks and 16 weeks |
| Change in SOLAR score | GSUS. 0 means the least synovitis and the maximum, PDUS, o means no PD and 3 the maximum | Baseline, 2 weeks and 16 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ahmed Elsaman | Sohag | 82749 | Egypt |
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| ID | Term |
|---|---|
| D001171 | Arthritis, Juvenile |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
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| ID | Term |
|---|---|
| D008012 | Lidocaine |
| D013256 | Steroids |
| ID | Term |
|---|---|
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 |
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double-blinded
| Placebo | Drug | an equivalent amount of saline will be injected subcutaneously in 2 points similar to the active group |
|
|
| Steroid | Drug | Intra-articular injection of 80mg of triamcinolone |
|
|
| D003240 |
| Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| Aniline Compounds |
| D000588 | Amines |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |