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To evaluate the long term outcomes of patients with thoracolumbar spondylodiscitis treated surgically by posterior approach.
Outcomes include bony fusion, neurological improvement, pain improvement, implant related complication, recurrence of infection and or reoperation rate
spondylodiscitis is characterized by infection that primarily affects the intervertebral disc and adjacent vertebrae. The estimated incidence of spondylodiscitis, ranging from 0.2 to 10 per 100,000 inhabitants per year, has increased in recent years, which is likely associated with an aging population, higher prevalence of chronic disease, and more effective diagnostic techniques. Spondylodiscitis is a life-threatening disease with a mortality rate of 2-20% that is often associated with potential complications, such as paraspinal abscess, epidural abscess, meningitis, spinal instability, and neurologic deficiency. The relapse rates were reported to be as high as 32% in the literature. The aims of this study are to evaluate improvements, complications, recurrence and reoperation rates in Assiut university hospitals.
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| Measure | Description | Time Frame |
|---|---|---|
| Bony fusion success | the degree of bridging bone across the fused vertebral bodies by using x-ray, CT scan and MRI if needed | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| modified Oswestry disability index | for patient quality of life postoperative | 2 years |
| visual analogue scale | the amount of pain sensed by the patient pre and post-operative |
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Inclusion Criteria:
• All patients had thoracolumbar spondylodiscitis from number 1 thoracic vertebra till number 1 sacral vertebra.
Exclusion Criteria:
• Patients with incomplete follow up.
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All Patients suffered from thoracolumbar spondylodiscitis and treated surgically by posterior approach in Assiut university hospitals from January 2016 to December 2017
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Micheal B Elia, resident | Contact | 01282682989 | +2 | mikelbassem@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Essam M Abdelmoneim Elmorshidy, Lecturer | Assiut University | Principal Investigator |
| El Moataz A Zohny El Sabrout, professor | Assiut University | Study Chair |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32057290 | Background | Kamal AM, El-Sharkawi MM, El-Sabrout M, Hassan MG. Spondylodiscitis: experience of surgical management of complicated cases after failed antibiotic treatment. SICOT J. 2020;6:5. doi: 10.1051/sicotj/2020002. Epub 2020 Feb 14. | |
| 26229122 | Background | Berbari EF, Kanj SS, Kowalski TJ, Darouiche RO, Widmer AF, Schmitt SK, Hendershot EF, Holtom PD, Huddleston PM 3rd, Petermann GW, Osmon DR, Infectious Diseases Society of America. 2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults. Clin Infect Dis. 2015 Sep 15;61(6):e26-46. doi: 10.1093/cid/civ482. Epub 2015 Jul 29. |
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| ID | Term |
|---|---|
| D015299 | Discitis |
| D013166 | Spondylitis |
| ID | Term |
|---|---|
| D001850 | Bone Diseases, Infectious |
| D007239 | Infections |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
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| 2years |
| American spinal injury Association (ASIA) Impairment score | to asses neurological outcomes pre operative and at 2 years follow up. | 2 years |
| Belal O Mohamed Elnady, Lecturer |
| Assiut University |
| Principal Investigator |
| 22072401 | Background | El-Sharkawi MM, Said GZ. Instrumented circumferential fusion for tuberculosis of the dorso-lumbar spine. A single or double stage procedure? Int Orthop. 2012 Feb;36(2):315-24. doi: 10.1007/s00264-011-1401-9. Epub 2011 Nov 10. |
| D013122 |
| Spinal Diseases |