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Intraocular surgery could induce vitreous degeneration and then abnormal posterior vitreous detachment (PVD) could occur including vitreoschisis and partial-thickness PVD. Vitreomacular interface (VMI) abnormalities such as epimacular membrane were observed following many intraocular surgeries. The incidence of peripheral break and epimacular membrane (EMM) after pneumatic retinopexy were 11.7% and 4-11%, respectively. Although multiple intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections induced PVD of 5.6%, but peripheral break was reported as only 0.67%. The incidence of rhegmatogenous retinal detachment (RRD) after phacoemulsification is gradually increased with time. The accumulative risk of RRD was increased from 0.27% at 1 year to 1.27% at 20 years after phacoemulsification.
The most common intraocular surgery is cataract surgery. From the literature review, many methods were used to detect the PVD after phacoemulsification. The former studies used indirect ophthalmoscopy and ocular ultrasound for diagnosis of PVD. The later studies used the optical coherence tomography (OCT) for PVD detection. The OCT device had higher effectiveness in evaluation of the posterior segment, and then it can detect post-phacoemulsification PVD more and early than previous studies. Ivastinovic et al demonstrated 59.2% of patients had PVD at 1 month after phacoemulsification, and increased up to 71.4% at 3 months.
Tsukahara et al introduced wide-field OCT-based PVD classification. The advance OCT device will be useful in detection of abnormal PVD and it's sequelae. If the risk factors of post-phacoemulsification PVD were explored, the prevention of abnormal PVD and VMI disorders could be done.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cataract patients who was scheduled for phacoemulsification | Other | Wide-field optical coherence tomography was performed before the surgery, and then was done at 1, 3, 6 and 12 months following the phacoemulsification. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Wide-field optical coherence tomography (Optovue®) | Device | Merged 4 images for wide-filed OCT-based PVD classification, 2 vertical line images and 2 horizontal line images |
|
| Measure | Description | Time Frame |
|---|---|---|
| The incidence of PVD after phacoemulsification | incidence of complete PVD | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| The incidence of VMI disorders | e.g. Epimacular membrane, Vitreomacular traction, Peripheral retinal break | 12 months |
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Withdrawal Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Suthasinee Sinawat, MD | Contact | +66 81 5454594 | ssuthasinee@kku.ac.th |
| Name | Affiliation | Role |
|---|---|---|
| Suthasinee Sinawat, MD | KKU Eye Center, Department of Ophthalmology, Faculty of Medicine, Khon Kaen University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Khon Kaen University | Recruiting | Khon Kaen | 40002 | Thailand |
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| ID | Term |
|---|---|
| D020255 | Vitreous Detachment |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
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