Dextrose Effect on Postoperative Nausea and Vomiting (PONV)

The Impact of Timing and Dosing of Dextrose Solution on Postoperative Nausea and Vomiting.

The aim of this study to assess which time and dose of dextrose solution more effective in decreasing postoperative nausea and vomiting.

All patients signed informed consent after excluding patients not candidate for the study.patients were divided to three groups, taking either 0.9% saline as control group(group C), dextrose 5%(group D5) or dextrose 10%(group D10).

Inclusion Criteria:

• Female non-smokers adults (age 18-65 years)
• ASA I-II who were listed for elective surgery under general anesthesia (surgery which is risk for PONV).

Exclusion Criteria:

• Severe hypertension
• Coagulopathy
• Significant hepatic or renal disease
• Diabetes mellitus or abnormal blood glucose on the morning of surgery
• Withdrawal of consent
• Severe intraoperative hypotension requiring large volume intravascular fluid treatment
• Protocol violations including nitrous oxide administration.