The Role of Fitostimoline Proctogel in Symptoms Relief and Healing in Patients Affected by Anal Fissure

The Role of Fitostimoline Proctogel in Symptoms Relief and Healing in Patients Affected by Anal Fissure

Evaluate the effectiveness of fitostimoline proctogel in the anal fissure healing and in the need for invasive interventions (primary endpoints) and in the healing of the fissure (secondary endpoint) using Fitostimoline in addition to or without other topical devices available on the market.

Three groups will be established: one for the exclusive use of fitostimoline, the second for the use of fitostimoline in addition to one of the other topical devices already on the market and the third group only for the use of other topical therapies.

Inclusion Criteria:

• None previous therapies for anal fissure
• Symptomatic anal fistula
• Signing of informed consent
• age >18 years old

Exclusion Criteria:

• Patients unable to complete the questionnaire and with a legal guardian.
• Patients with concomitant abscess/fistula
• Pregnant women