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Staphylococcus aureus osteoarticular infections, in particular those associated with the presence of implant, relapse in 20% of cases. Currently, the reasons for these relapses are poorly understood, whether on the microbiological or clinical side.
The aim of this study is to improve knowledge on persistence of mechanisms of S. aureus
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| relapse due to S. aureus | patients having had an initial infection due to S. aureus and who present a relapse with persistence of S. aureus |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| relapse due to S. aureus | Other | to find out if it is the same S. aureus in both infections |
|
| Measure | Description | Time Frame |
|---|---|---|
| rate of patients having had an osteoarticular infection due to S. aureus | proportion of patients having had an osteoarticular infection due to S. aureus | between 2015 and 2020 |
| Description of patients having had an osteoarticular infection due to S. aureus | type of patients: age, BMI, comorbidities... | between 2015 and 2020 |
| Description of Bone and Joint Iinfection/Prosthesis Joint Infection | implant or prosthesis or not, acute/ chronic, bacteriology | between 2015 and 2020 |
| Measure | Description | Time Frame |
|---|---|---|
| rate of patients having had a relapse due to persistence of S. aureus | proportion of patients having had an osteoarticular infection due persistence of S. aureus | between 2015 and 2020 |
| rate of S. aureus strain identical between the initial episode and the relapse |
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Inclusion Criteria:
Exclusion Criteria:
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patients having had an osteoarticular infection with or without material due to S. aureus and treated at CRIOAc Lyon, presenting a recurrence of S. aureus infection
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Eugenie Mabrut, CRA | Contact | 04 26 73 29 38 | eugenie.mabrut@chu-lyon.fr | |
| Tristan Ferry, MD,PhD | Contact | 04 26 73 29 38 | tristan.ferry@chu-lyon.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospices Civils de Lyon | Recruiting | Lyon | 69004 | France |
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| Label | URL |
|---|---|
| Related Info | View source |
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| ID | Term |
|---|---|
| D013203 | Staphylococcal Infections |
| D012008 | Recurrence |
| ID | Term |
|---|---|
| D016908 | Gram-Positive Bacterial Infections |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
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proportion of relapse due to the same strain of S. aureus than in the initial episode |
| between 2015 and 2020 |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |