Utility of Hyperpolarized 13C-pyruvate Metabolic Magnetic Resonance Imaging

Utility of Hyperpolarized 13C-pyruvate Metabolic Magnetic Resonance Imaging in the Diagnosis and Risk-Stratification of Prostate Cancer

This is a two-tiered pilot study in which there will be no randomization and no placebo treatment. This study will be to perform metabolic magnetic resonance imaging on men suspected to have a prostate cancer to understand if metabolic MRI can be safely performed on this population

Inclusion Criteria:

1. Age greater than 40 and less than 80 years

2. Clinical suspicion or history of prostate cancer reflected by one of the following:

   • PSA > 4ng/ml
   • Abnormal DRE exam
   • Known tissue diagnosis of prostate cancer from prior workup

3. Patient planning to undergo either a MRI targeted biopsy or radical prostatectomy for prostate cancer workup or treatment

Exclusion Criteria:

1. Inability to undergo MRI scan
2. Inability to receive IV contrast as per institutional protocol.