Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
There are many conservative treatment options available for partial rotator cuff tears. However, the superiority of a certain type of injection could not be demonstrated with the available data. Our aim is to compare the effectiveness of steroid, hyaluronic acid, prp and placebo (normal saline) injections in partial rotator cuff tears by applying the same physical therapy protocol after injection.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hyaluronic Acid + Physical Therapy | Experimental | 4 ml hyaluronic acid (subacromial) |
|
| Platelet-Rich-Plasma (PRP) + Physical Therapy | Experimental | 4 ml platelet-rich-plasma (subacromial) |
|
| Steroid + Physical Therapy | Experimental | methylprednisolone acetate (1ml methylprednisolone acetate + 3 ml serum saline) (subacromial) |
|
| Placebo (serum saline) + Physical Therapy | Experimental | 4 ml serum saline (subacromial) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Subacromial Injection (hyaluronic acid) + Physical Therapy. | Combination Product | arm1: sodium hyaluronate (4ml) arm2: platelet-rich-plasma (4ml) arm3: methylprednisolone acetate (1ml methylprednisolone acetate + 3 ml serum saline) arm4: serum saline (4ml) The same physical therapy procedure will be applied to all arms after injection. |
| Measure | Description | Time Frame |
|---|---|---|
| American Shoulder and Elbow Surgeons Shoulder Score (ASES) | minimum score:0, maximum score:100, 100 is better function. | 12 months after injection |
| Measure | Description | Time Frame |
|---|---|---|
| Constant-Murley Shoulder Outcome Score (CMS) | minimum score:0, maximum score:100, 100 is better function. | 12 months after injection |
| Visual analogue scale (VAS) | minimum score:0, maximum score:10, 0 is better function |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bezmialem Vakif University | Istanbul | 34093 | Turkey (Türkiye) | |||
| Bezmialem Vakif University |
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Subacromial Injection (Platelet-Rich-Plasma) + Physical Therapy. | Combination Product | arm1: sodium hyaluronate (4ml) arm2: platelet-rich-plasma (4ml) arm3: methylprednisolone acetate (1ml methylprednisolone acetate + 3 ml serum saline) arm4: serum saline (4ml) The same physical therapy procedure will be applied to all arms after injection. |
|
| Subacromial Injection (methylprednisolone acetate) + Physical Therapy. | Combination Product | arm1: sodium hyaluronate (4ml) arm2: platelet-rich-plasma (4ml) arm3: methylprednisolone acetate (1ml methylprednisolone acetate + 3 ml serum saline) arm4: serum saline (4ml) The same physical therapy procedure will be applied to all arms after injection. |
|
| Subacromial Injection (Serum Saline) + Physical Therapy. | Combination Product | arm1: sodium hyaluronate (4ml) arm2: platelet-rich-plasma (4ml) arm3: methylprednisolone acetate (1ml methylprednisolone acetate + 3 ml serum saline) arm4: serum saline (4ml) The same physical therapy procedure will be applied to all arms after injection. |
|
| 12 months after injection |
| Subjective Shoulder Value (SSV) | minimum score:0, maximum score:100, 100 is better function. | 12 months after injection |
| Range of Motion (ROM) | Active Shoulder Range of Motion Measurements | 12 months after injection |
| Istanbul |
| 34093 |
| Turkey (Türkiye) |
|
| ID | Term |
|---|---|
| D000070636 | Rotator Cuff Injuries |
| ID | Term |
|---|---|
| D012421 | Rupture |
| D014947 | Wounds and Injuries |
| D000070599 | Shoulder Injuries |
| D013708 | Tendon Injuries |
Not provided
Not provided
| ID | Term |
|---|---|
| D006820 | Hyaluronic Acid |
| D026741 | Physical Therapy Modalities |
| D000077555 | Methylprednisolone Acetate |
| ID | Term |
|---|---|
| D006025 | Glycosaminoglycans |
| D011134 | Polysaccharides |
| D002241 | Carbohydrates |
| D013812 | Therapeutics |
| D012046 | Rehabilitation |
| D008775 | Methylprednisolone |
| D011239 | Prednisolone |
| D011246 | Pregnadienetriols |
| D011245 | Pregnadienes |
| D011278 | Pregnanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
Not provided
Not provided