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The aim of the study is to establish an infectious risk stratification system based on pre-and post-operative blood endotoxin profile.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| endotoxin study group | Patients scheduled for Percutaneous Nephrolithotomy (PCNL) as surgical treatment for their kidney stones will be evaluated for postoperative endotoxin levels as a risk marker for sepsis. |
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| Measure | Description | Time Frame |
|---|---|---|
| Number of participants at each endotoxin activity level after surgery. | The endotoxin activity level assessed from blood samples will be categorized as low (<0.40), intermediate (0.40-0.59) or high (≥0.60) endotoxin activity level. Analysis will be done via Endotoxin Activity Assay (EAA). | Day 1 (within 30 minutes postoperative) |
| Corelation of endotoxin activity level with post-operative infectious complication | infectious complications include fever, and signs and symptoms of systemic inflammatory response syndrome as evaluated by treating physician. | up to 24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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Patients scheduled for PCNL as surgical treatment for their kidney stones at Jackson and the University of Miami Hospitals.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hemendra N Shah | Contact | 3052433246 | hns35@miami.edu |
| Name | Affiliation | Role |
|---|---|---|
| Hemendra N Shah | University of Miami | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Miami | Recruiting | Miami | Florida | 33136 | United States |
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| ID | Term |
|---|---|
| D053040 | Nephrolithiasis |
| D005334 | Fever |
| ID | Term |
|---|---|
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052878 | Urolithiasis |
| D052801 | Male Urogenital Diseases |
| D001832 | Body Temperature Changes |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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