Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| RDB Bioinformatics | INDUSTRY |
| University of Iowa | OTHER |
| Trustees of Dartmouth College | OTHER |
Not provided
Not provided
Not provided
Not provided
Healthcare-associated infections (HAIs) occur frequently and are associated with patient harm. It is important that healthcare facilities take the necessary steps to prevent the spread of resistant bacteria. ESKAPE bacteria (Enterococcus, S. aureus, Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter spp.) are particularly pathogenic. Isolation of these pathogens from intraoperative reservoirs has been associated with postoperative infection development (i.e. surgical site infections). This project involves implementation of a software platform and bacterial collection system (OR PathTrac) that leverages the epidemiology of intraoperative bacterial transmission to guide dynamic, prospective improvements in perioperative infection control measures. The investigators will assess the effectiveness of OR PathTrac feedback in optimizing an evidence-based, multifaceted, perioperative infection control program.
Our objective was to analyze the impact of surveillance feedback optimization of a multifaceted, perioperative infection control program on S. aureus transmission and SSIs. A multifaceted infection control program was implemented over 8 months (November 2018 to June 2019). A prospective cohort impact study was then conducted over 8 months (July 2019 to March 2020) to compare the incidence of within-case S. aureus transmission (primary outcome) and surgical site infection (secondary outcome) before (4.5 months) and after (3.5 months) implementation of surveillance feedback.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Before OR PathTrac Feedback | Patients undergoing surgery with an evidence-based, multifaceted, perioperative infection control program in place but without OR PathTrac feedback optimization. | ||
| After OR PathTrac Feedback | Patients undergoing surgery with an evidence-based, multifaceted, perioperative infection control program in place AND OR PathTrac feedback optimization. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| OR PathTrac Feedback Optimization | Other | OR PathTrac (RDB Bioinformatics, Omaha, NE 68154) uses a systematic phenotypic approach leveraging temporal association to monitor 13 anesthesia work area reservoirs proven to be associated with high-risk intraoperative bacterial transmission events and subsequent infection development. |
| Measure | Description | Time Frame |
|---|---|---|
| within-case S. aureus transmission | S. aureus transmission events detected within a surgical case | From patient entry into the operating room until case end, up to 6 hours |
| Measure | Description | Time Frame |
|---|---|---|
| surgical site infection | evidence of infection (office note documentation with anti-infective order and/or isolation of one or more potentially pathogenic organisms | Up to 90 days following surgery |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Adult patients undergoing surgery requiring anesthesia and intravascular access.
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Georgetown University | Georgetown | District of Columbia | 20057 | United States |
Other researchers must submit a research proposal to be reviewed by Dr. Wall for determination of release.
One year after publication the data will become available and will remain available for one year.
Submission of a research proposal to be reviewed by Dr. Wall.
Not provided
Not provided
| ID | Term |
|---|---|
| D013530 | Surgical Wound Infection |
| D013203 | Staphylococcal Infections |
| ID | Term |
|---|---|
| D014946 | Wound Infection |
| D007239 | Infections |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
Not provided
Not provided
Not provided
Not provided
Not provided
S. aureus pathogens collected were assigned a unique identification number and stored for future analysis.
|
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D016908 | Gram-Positive Bacterial Infections |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |