Due to the COVID-19 era, clinical research was interrupted, and this study was terminated.

The first patient in the dyad will receive the bundle, which includes patient decolonization methods, environmental cleaning in the OR, a hand hygiene system located on the IV pole for the anesthesia provider, and intravascular catheter and syringe tip disinfection practices. The second patient in the dyad will receive usual care. Both patients will be surveyed by obtaining swab samples at the beginning and end of the surgery using the OR PathTrac kits. The OR PathTrac software (RDB Bioinformatics, Omaha, NE 68154) uses algorithms to guide analysis of the S. aureus isolates and to identify transmission events. Transmission stories are processed by the software to generate transmission maps that identify improvement successes and failures. It also identifies actionable steps to improve the bundle. The perioperative infection control team then uses this information to continually optimize the bundle, and the software to measure the effect.

Surgical site infections increase patient morbidity and healthcare costs. The Centers for Disease Control and Prevention emphasizes improved basic preventive measures to reduce bacterial transmission and infections for patients undergoing surgery.

Patients undergoing planned oncologic gynecological and plastic surgery will be entered as dyads into a worksheet each day that will rank and select the optimal cases. The research assistants consent both patients in the dyad to the study while they are in the Day of Surgery Admissions area. The first patient in the dyad will receive the bundle, which includes patient decolonization methods, environmental cleaning in the OR, a hand hygiene system located on the IV pole for the anesthesia provider, and intravascular catheter and syringe tip disinfection practices. The second patient in the dyad will receive usual care. Both patients will be surveyed by obtaining swab samples at the beginning and end of the surgery using the OR PathTrac kits. The OR PathTrac kits are obtained from and analyzed for S. aureus isolates by RDB Bioinformatics. The OR PathTrac software (RDB Bioinformatics, Omaha, NE 68154) uses algorithms to guide analysis of the S. aureus isolates and to identify transmission events. Transmission stories are processed by the software to generate transmission maps that identify improvement successes and failures. It also identifies actionable steps to improve the bundle. The perioperative infection control team then uses this information to continually optimize the bundle, and the software to measure the effect.

Inclusion Criteria:

• Patients scheduled to undergo oncologic gynecological and plastic surgery requiring general/regional anesthesia.
• informed, written consent.

Exclusion Criteria:

• Patients <18 years of age.
• Patients scheduled to undergo procedures outside of the surgical service lines listed above.
• Patients not requiring general or regional anesthesia.
• Patients who have a documented allergy or have an allergic reaction to to iodine, shellfish, or chlorhexidine.
• Patients who have not provided informed, written consent.

Patients scheduled to undergo oncologic gynecological and plastic surgery requiring general/regional anesthesia.

Data will be shared upon written request and reviewed by the principal investigator for consideration.

Upon request and evaluation, if approved by the PI for release, at least one year from publication date.

Submitted research protocol approved by the principal investigator, Dr. Loftus