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Postoperative pancreatic fistula(POPF) is the most common complication of pancreaticoduodenectomy (PD). Sometimes POPF is associated with biliary fistula(BF), or "mixed" fistula. The purpose of this study is to assess whether the severity of the fistulae, when present, is decreased with an external biliary stent in place.
n this single-center study we analyze patients who underwent elective PD from January_2014 to December_2017. Patients are divided into two groups: standard PD (ST-PD)vs PD with external biliary stent(PD-BS). Demographic, preoperative, intraoperative, and postoperative variables will be analyze, including complications according to the Clavien-Dindo classification, and those specific to pancreatic surgeries, and mortality rates within 90 days of operation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| standard PD (ST-PD) | Pancreacoduodenectomy with pancreatic-enteric reconstruction and standard hepaticojejunostomy | ||
| PD with external biliary stent(PD-BS) | Pancreacoduodenectomy with pancreatic-enteric reconstruction and hepaticojejunostomy with external biliary stent for externalization of bile fluid |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| External biliary stent | Procedure | The biliary stent consisted of a multi-perforated, natural rubber tube, measuring 3.5 mm in diameter, that we placed transanastomotically, with exteriorization sited at 20 cm utilizing the Witzel jejunostomy approach |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative complications | Any postoperative complications | 90 days |
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Inclusion Criteria:
Exclusion Criteria:
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Patients undergo elective pancreaticoduodenectomy
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| Name | Affiliation | Role |
|---|---|---|
| Gerardo Blanco-Fernández, MD, PhD | Universidad de Extremadura | Study Director |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33768426 | Derived | Blanco-Fernandez G, Jaen-Torrejimeno I, De-Armas-Conde N, Rojas-Holguin A, Naharro JS, Castillo-Tunon JM, Lopez-Guerra D. Prospective Study Correlating External Biliary Stenting and Pancreatic Fistula Following Pancreaticoduodenectomy. J Gastrointest Surg. 2021 Nov;25(11):2881-2888. doi: 10.1007/s11605-021-04983-6. Epub 2021 Mar 25. |
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| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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