Exploratory Study: COVID-19 and Pregnancy

Exploratory Study in COVID-19 During Pregnancy

The SARS-CoV-2 infection may behave differently in pregnant and postpartum women in the short and long term. Several risk factors or medication use can interfere on disease' evolution and vertical transmission. Thus, due the current pandemic and the scarcity of scientific studies involving pregnant women with covid-19 or positive serology, combined with the need to elucidate the behavior of this viral infection in pregnant women in our population, this study aims to evaluate the clinical and laboratory evolution, transplacental passage, gestational and neonatal outcomes in pregnancies with positive SARS-CoV-2.

Inclusion Criteria:

• Pregnant women with clinical symptoms or positive serology for SARS-CoV-2 hospitalized or in delivery time;
• Asymptomatic pregnant women for SARS-CoV-2 during pregnancy and hospitalized for delivery at HU-USP.
• Pregnant women diagnosed with SARS-CoV-2 prior to delivery and who, after the quarantine period, followed prenatal care and delivered at the HU-USP or HCFMUSP.

Exclusion Criteria:

• Non-confirmation of maternal SARS-CoV-2 infection in pregnant women hospitalized or in delivery time.
• Withdrawal of pregnant woman to continue in the study.