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| ID | Type | Description | Link |
|---|---|---|---|
| 2019-A02651-56 | Other Identifier | ID-RCB number,ANSM |
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| Name | Class |
|---|---|
| Groupement Interrégional de Recherche Clinique et d'Innovation | OTHER |
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Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), ulcerative colitis (UC) and IBD-unclassified (IBD-U), are characterised by chronic inflammation of the gastrointestinal tract. Over the past 50 years, the incidence of IBD has increased globally, with the highest increase in industrialised countries. During the last 25 years, the incidence of IBD has increased dramatically among teenagers in northern France, with an increase of 126% and 156% for CD and UC, respectively.
Physical fitness is a set of attributes related to a person's ability to perform physical activities that require aerobic capacity, endurance, strength or flexibility and is determined by a combination of regular physical activity and genetically inherited ability. Physical fitness, widely recognised as an important health determinant, plays an important role in growth and development. Due to the evidence-based importance of physical fitness for young people's health status, attention should be paid to the assessment of physical fitness at these ages and whatever the health status.
At this time, there is no study on the assessment of physical fitness in IBD pediatric patient.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Child with IBD |
| ||
| Healthy child witnesses |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| GT3X Actigraph accelerometer. | Device | GT3X Actigraph accelerometer during 7 days |
|
| Measure | Description | Time Frame |
|---|---|---|
| Difference in cardiorespiratory fitness (expressed in ml/kg/min) between children and adolescents with IBD and age-, BMI and sex-matched healthy controls. | At 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Difference in muscular endurance, strength, speed/agility, flexibility, strength between children and adolescents with IBD and age-, BMI and sex-matched healthy controls | Baseline, at 7 days | |
| Disease activity according to PCDAI scores | (Pediatric Crohn Disease Activity Index) |
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Inclusion Criteria:
For healthy controls:
Exclusion Criteria:
For healthy controls:
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Healthy children and adolescents with IBD (Crohn's disease, ulcerative colitis and chronic ulcerative colitis).
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| Name | Affiliation | Role |
|---|---|---|
| Dominique TURCK, MD,PhD | University Hospital, Lille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hop Jeanne de Flandre Chu Lille | Lille | 59037 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36220315 | Result | Vanhelst J, Beghin L, Coopman S, Labreuche J, Djeddi D, Gottrand F, Turck D, Ley D. Physical fitness in children and adolescents with inflammatory bowel disease: protocol for a case-control study. BMJ Open. 2022 Oct 11;12(10):e063403. doi: 10.1136/bmjopen-2022-063403. |
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Data are available upon reasonable request. Data will be made available following the conclusion of the project's period of funding.
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| Baseline, at 7 days |
| Disease activity according to PUCAI scores | Pediatric Ulcerative Colitis Activity Index | Baseline, at 7 days |
| Percentage of IBD children and adolescents with a cardiovascular risk disease | Baseline, at 7 days |
| Correlation between quality of life and physical fitness in children and adolescent with IBD | Baseline, at 7 days |
| Correlation between fatigue and physical fitness in children and adolescent with IBD | Baseline, at 7 days |
| Correlation between daily physical activity and physical fitness in children and adolescent with IBD | Baseline, at 7 days |
| ID | Term |
|---|---|
| D003424 | Crohn Disease |
| D015212 | Inflammatory Bowel Diseases |
| D003093 | Colitis, Ulcerative |
| D011350 | Proctocolitis |
| ID | Term |
|---|---|
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D007410 | Intestinal Diseases |
| D003092 | Colitis |
| D003108 | Colonic Diseases |
| D011349 | Proctitis |
| D012810 | Sigmoid Diseases |
| D012002 | Rectal Diseases |
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