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| Name | Class |
|---|---|
| KK Women's and Children's Hospital | OTHER_GOV |
| Singapore Health Services | OTHER |
| Duke-NUS Graduate Medical School | OTHER |
| Cardiff University |
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Singapore, like many developed countries, is experiencing low birth rates, which is coupled with increasing age at first marriage and birth. In addition, demand for assisted reproduction technology treatments has increased over the years. Fertility awareness surveys have consistently shown that public awareness of age-related fertility decline and the limitations of fertility treatments is generally low, and this may lead to couples not optimising their fertility potential to achieve their family aspirations. This trial aims to study the effect of fertility health screening and fertility awareness tools on knowledge, attitudes and practice around childbearing among young Singaporean married couples.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fertility Health Screening | Active Comparator | Clinic-based fertility health screening and counselling |
|
| Fertility Awareness Tools | Active Comparator | Online intervention to provide fertility education and behavioural nudge for optimal reproductive timing. |
|
| Control | No Intervention | No intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fertility Health Screening | Diagnostic Test | Basic fertility health screening comprising an anti-Mullerian hormone (AMH) test and semen analysis, a doctor's consultation to explain the results, and standardised reproductive counselling by a trained nurse comprising a discussion of reproductive plans (including addressing barriers the couple face), education on age-related fertility decline and limitations of artificial reproductive technologies, advice on the optimal reproductive timing and when to seek further help. An educational brochure will be handed to the couple during the counselling session. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in parenthood intentions | The difference in the female partner's intended age at first birth at 6 months post-randomization compared to baseline, elicited by a direct question in pre and post-questionnaires. | Baseline (before intervention) and 6 months later |
| Measure | Description | Time Frame |
|---|---|---|
| Change in fertility awareness | The difference in fertility awareness as measured by the Cardiff Fertility Knowledge Scale (CFKS) at 6 months post-randomization compared to baseline. The CFKS is a 13-item scale where each correct answer is assigned 1 point. Points are summed and converted to the % correct fertility knowledge score with a range of 0 - 100%. | Baseline (before intervention) and 6 months later |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Singapore General Hospital | Singapore | 169608 | Singapore | |||
| KK Women's and Children's Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34980614 | Derived | Chan SL, Thumboo J, Boivin J, Saffari SE, Yin S, Yeo SR, Chan JKY, Ng KC, Chua KH, Yu SL. Effect of fertility health awareness strategies on fertility knowledge and childbearing in young married couples (FertStart): study protocol for an effectiveness-implementation hybrid type I multicentre three-arm parallel group open-label randomised clinical trial. BMJ Open. 2022 Jan 3;12(1):e051710. doi: 10.1136/bmjopen-2021-051710. |
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| OTHER |
| National Population and Talent Division | UNKNOWN |
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|
| Fertility Awareness Tools | Behavioral | Online intervention consisting of 1) video targeting fertility education and specific attitudes, social norms and perceived control for having children, 2) a fertility awareness tool (FERTISTAT) and 3) an educational brochure on fertility. This intervention can be self-administered and is therefore easily scalable. |
|
| Conception efforts | Proportion of couples who are (a) attempting to conceive, (b) pregnant, (c) who pursued more comprehensive fertility screening and/or (d) who pursued fertility treatment. | 6 moths post-randomization |
| Birth number | Number of births | 2 and 3 years post-randomization |
| Birth timing | Time to first birth | 2 and 3 years post-randomization |
| Singapore |
| 229899 |
| Singapore |
| ID | Term |
|---|---|
| D001519 | Behavior |
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