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To follow up the progress of chronic complications in T2DM patients who had undergone anthropometric measurements, laboratory testing and standard overnight polysomnography monitor from 2013 to 2018.
Obstructive sleep apnea (OSA) is a common chronic sleep disorder and a frequent comorbidity in patients with type 2 diabetes. There has been increasing recognition that OSA is highly prevalent in persons with type 2 diabetes. This study is to explore the relationship between OSA and the progress of chronic diabetes-related complications in type 2 diabetes who had undergone anthropometric measurements, laboratory testing and standard overnight polysomnography monitor from 2013 to 2018 in the Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, Xiamen, China.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| T2DM with OSA | Type 2 diabetes patients with obstructive sleep apnea |
| |
| T2DM without OSA | Type 2 diabetes patients without obstructive sleep apnea |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| regular treatment | Other | The patients with or without OSA received regular hypoglycemic drugs. |
|
| Measure | Description | Time Frame |
|---|---|---|
| the progress of diabetic complications | Diabetic complications include diabetic microvascular complications, atherosclerotic cardiovascular disease(ASCVD), and Diabetic foot disease. Diabetic microvascular complications include diabetic nephropathy, diabetic retinopathy and diabetic neuropathy. Diabetic macrovascular complications refer to ASCVD, which is defined as coronary heart disease (CHD; acute and silent MI, and unstable angina), ischemic stroke, or peripheral artery disease (PAD). | From January 1, 2013 to December 31, 2020 |
| the new onset and types of tumor in T2DM patients | the new onset and types of tumor in T2DM patients | From January 1, 2013 to December 31, 2020 |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with Type 2 diabetes
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Changqin Liu, Dr. | Contact | +86-592-2137796 | liuchangqin@xmu.edu.cn | |
| Xin Zheng | Contact | +86-592-2137796 | 88126386@qq.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The first affiliated hospital of Xiamen university | Recruiting | Xiamen | Fujian | 361003 | China |
The datasets used and/or analyzed in this cohort are available from the corresponding author on reasonable request.
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| ID | Term |
|---|---|
| D048909 | Diabetes Complications |
| D020181 | Sleep Apnea, Obstructive |
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D004700 | Endocrine System Diseases |
| D012891 | Sleep Apnea Syndromes |
| D001049 | Apnea |
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| D012120 |
| Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D020919 | Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D009422 | Nervous System Diseases |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |