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The purpose of this study is to evaluate the optimization of MRI acquisition sequences.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| All subjects will have an MRI examination | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI examination | Other | All subjects (healthy subjects and patients) will have an MRI examination with optimized sequences |
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| Measure | Description | Time Frame |
|---|---|---|
| Image quality based on standard imaging quality criteria. | The image quality will be appreciated visually at least by a radiologist or a researcher. | 6 months after the last inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of the Signal to Noise Ratio obtained by the optimized MRI sequence and the reference situation (standard sequence). | Signal to Noise Ratio will be measured in arbitrary units. | 6 months after the last inclusion |
| Comparison of the Contrast to Noise Ratio obtained by the optimized MRI sequence and the reference situation (standard sequence). |
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Inclusion Criteria for all subjects :
Inclusion Criteria especially for Patients :
Exclusion Criteria for all subjects :
Exclusion Criteria especially for Healthy Subjects :
Exclusion Criteria especially for Patients :
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Valérie LAURENT, MD, PhD | Contact | +33383154181 | v.laurent@chru-nancy.fr | |
| Gabriela HOSSU, PhD | Contact | +33383155096 | g.hossu@chru-nancy.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHRU de Nancy | Recruiting | Nancy | 5400 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38997324 | Result | He Z, Soullie P, Lefebvre P, Ambarki K, Felblinger J, Odille F. Changes of in vivo electrical conductivity in the brain and torso related to age, fat fraction and sex using MRI. Sci Rep. 2024 Jul 12;14(1):16109. doi: 10.1038/s41598-024-67014-9. | |
| 36173349 | Result | Caron B, Laurent V, Odille F, Danese S, Hossu G, Peyrin-Biroulet L. New magnetic resonance imaging sequences for fibrosis assessment in Crohn's disease: a pilot study. Scand J Gastroenterol. 2022 Dec;57(12):1450-1453. doi: 10.1080/00365521.2022.2094727. Epub 2022 Sep 29. |
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Contrast to Noise Ratio will be measured in arbitrary units. |
| 6 months after the last inclusion |
| Comparison of the acquisition time obtained with the optimized MRI sequence and the reference situation (standard sequence). | Time acquisition will be evaluated in minutes. | 6 months after the last inclusion |
| Comparison of blurring and artefacts obtained by the optimized MRI sequence and the reference situation (standard sequence). | Absence of blurring and artefacts will be assessed by at least one radiologist according to an ordinal scale. | 6 months after the last inclusion |
| Comparison of the spatial resolution obtained by the optimized MRI sequence and the reference situation (standard sequence). | Spatial resolution will be measured in mm². | 6 months after the last inclusion |
| Qualification of the MRI acquisition for a clinical study. | Validation of MRI acquisition by a centralized review center. | 6 months after the inclusion |
| Evaluation of intra-subject reproducibility on the same MRI and on two MRIs. | Measurement of intra-subject reproducibility on the same MRI and on two MRIs by the intra-class correlation coefficient for quantitative measurement or by the kappa coefficient for a qualitative measurement. | 6 months after the last inclusion |
| 40876943 | Result | Boubaker F, Lane JI, Puel U, Drouot G, Witte RJ, Ambarki K, Gondim-Teixeira PA, Blum A, Parietti-Winkler C, Vallee JN, Gillet R, Eliezer M. High-Resolution 3T MRI of the Membranous Labyrinth Using Deep Learning Reconstruction. AJNR Am J Neuroradiol. 2026 Mar 4;47(3):723-729. doi: 10.3174/ajnr.A8989. |
| 41285050 | Result | Gillet R, Boubaker F, Clara M, Ambarki K, Stemmer A, Drouot G, Gillet P, Gondim Teixeira PA, Blum A. Optimizing knee MRI: 3D proton density turbo spin echo nDixon sequence vs. 2D high-resolution turbo spin echo in half the acquisition time. Eur J Radiol. 2026 Feb;195:112552. doi: 10.1016/j.ejrad.2025.112552. Epub 2025 Nov 19. |
| 37188883 | Result | Wary P, Hossu G, Ambarki K, Nickel D, Arberet S, Oster J, Orry X, Laurent V. Deep learning HASTE sequence compared with T2-weighted BLADE sequence for liver MRI at 3 Tesla: a qualitative and quantitative prospective study. Eur Radiol. 2023 Oct;33(10):6817-6827. doi: 10.1007/s00330-023-09693-y. Epub 2023 May 16. |
| 42338094 | Derived | Paillart G, He Z, Romero G, Ferry P, Ambarki K, Soullie P, Felblinger J, Odille F. Improved Radiofrequency Safety Modelling in MRI Using In Vivo Measurements of Brain Conductivity. NMR Biomed. 2026 Aug;39(8):e70335. doi: 10.1002/nbm.70335. |