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| Name | Class |
|---|---|
| Swiss National Science Foundation | OTHER |
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Subliminal perception of visual stimuli can be studied with functional brain imaging, e.g. with functional magnetic resonance imaging (fMRI). However, it is unclear how subliminal perception affects connectivity in the brain.
Further, it is not known if real-time (rt) fMRI neurofeedback of brain areas involved in subliminal perception can lead to supra-threshold perception.
For attention tasks, the investigators hypothesize that functional connectivity strength is mediated by the insular cortex during both supra-threshold and subliminal perception.
Additionally, the investigators hypothesize that rt-fMRI neurofeedback training should alter neuronal and behavioral responses.
In this project, using healthy adults, the investigators have 2 aims:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| active group 1 | This group will train the insular cortex by real-time fMRI |
| |
| active group 2 | This group will train the visual cortex by real-time fMRI |
| |
| sham | This group will only train the insula by a particular strategy |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| real-time fMRI | Other | Brain regions can be trained, i.e. fMRI activity can be actively modulated online by humans, using rt-fMRI (Bruhl, Scherpiet et al. 2014, Bruhl 2015, Emmert, Kopel et al. 2016). |
| Measure | Description | Time Frame |
|---|---|---|
| fMRI during supra-threshold and subliminal perception | 2020 - 2022 | |
| rt-fMRI activity | rt-fMRI activity: fMRI signal changes during repetitive real time fMRI based training | 2020 - 2022 |
| Measure | Description | Time Frame |
|---|---|---|
| Functional connectivity | Examination of fMRI signal dependencies (coherence) between brain regions. | 2020 - 2022 |
| EEG activity | EEG activity: Event related potentials and spectral band power for different trial types |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy adults
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| Name | Affiliation | Role |
|---|---|---|
| Lars Michels, PhD | University Hospital, Zürich | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Zurich | Zurich | Switzerland |
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| Label | URL |
|---|---|
| SNF database | View source |
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Raw imaging data can be shared with other groups (outside of the USZ), e.g. for replication purpose.
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| 2020 - 2022 |
| fMRI task performance | Reaction time and accuracy | 2020 - 2022 |