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| ID | Type | Description | Link |
|---|---|---|---|
| 2020-A01272-37 | Other Identifier | IDRCB |
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| Name | Class |
|---|---|
| UR 3072 - Mitochondrie, Stress oxydant et Protection musculaire | UNKNOWN |
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This is a transversal monocentric study comparing two groups of women (group 1, patient group : patients who have been treated for a breast cancer with taxane-based chemotherapy ; group 2, control group : healthy volunteers). The aim of this study is to evaluate if a difference exists regarding the maximal isometric muscle strength between group 1 and 2.
All subjects will be evaluated a single time during two hours. For patients from group 1 the evaluation should take place within the two weeks that follow the end of adjuvant treatment. There is no specificity regarding evaluation of volunteers from group 2, their evaluation can take place at any time.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 : Patients | Experimental |
| |
| Group 2 : healthy volunteers | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Characterization of Neuromuscular Function and Fatigue | Other | at inclusion |
|
| Measure | Description | Time Frame |
|---|---|---|
| Maximal isometric muscle strength for knee extensors | Measured with force sensors. Significant differences between the two groups will be assessed | At Inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants with neuromuscular fatigue | Assessment using surface electromyography. Significant differences between the two groups will be assessed. | At Inclusion |
| Number of Participants with neuromuscular fatigue |
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Inclusion Criteria :
Group 1 - Patients :
Group 2 - Control group :
Exclusion Criteria:
Group 1 - Patients :
Group 2 -Control group :
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institut de Cancerologie Strasbourg Europe | Strasbourg | 67033 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36939876 | Derived | Hucteau E, Mallard J, Pivot X, Schott R, Pflumio C, Trensz P, Favret F, Pagano AF, Hureau TJ. Exacerbated central fatigue and reduced exercise capacity in early-stage breast cancer patients treated with chemotherapy. Eur J Appl Physiol. 2023 Jul;123(7):1567-1581. doi: 10.1007/s00421-023-05177-5. Epub 2023 Mar 20. |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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Assessment using percutaneous electric nerve stimulation. Significant differences between the two groups will be assessed.
| At Inclusion |
| Number of Participants with neuromuscular fatigue | Assessment using transcranial magnetic stimulation. Significant differences between the two groups will be assessed. | At Inclusion |
| Number of Participants with subjective fatigue. | Questionnaire Functional Assessment of Chronic Illness Therapy - Fatigue Scale (FACIT-F) version 4. Significant differences between the two groups will be assessed. | At Inclusion |
| Number of Participants with muscle architecture. | Assessment using muscle ultrasonography. Significant differences between the two groups will be assessed. | At Inclusion |
| Number of Participants with body composition. | Assessment using bio-impedance analysis. Significant differences between the two groups will be assessed. | At Inclusion |
| D017437 |
| Skin and Connective Tissue Diseases |