Intermittent Hypoxia Intervention in MS Patients

Safety and Tolerance of an Intermittent Intervention in MS Patients

This observational cohort study investigates the safety and feasibility of an intermittent hypoxia intervention in multiple sclerosis.

Inclusion Criteria:

• 18-60 years
• confirmed MS (all types of MS)
• ability to come to the outpatient clinic 2-3x/week for 3 months
• EDSS ≤ 6.5
• inconspicuous medical examination
• inconspicuous ECG

Exclusion Criteria:

• relapse in the last 3 months
• EDSS progression in the last 6 months
• pregnancy
• contraindication for MRI
• severe heart disease
• severe asthma, COPD
• cancer
• severe cognitive deficits
• chronic headache
• renal insufficiency
• anaemia (Hb < 10 g/dl)
• insulin-dependent diabetes mellitus
• severe vascular stenosis
• former episodes of severe high mountain sickness
• cancer