A Multidisciplinary Intervention for Weight Loss

Efficacy and Safety of a Long-term Multidisciplinary Weight Loss Intervention in Patients With Obesity: an Open Label Study

This is an open label study in which obese participants were treated with a restrictive hypo-caloric diet under hospitalization for a maximum period of 3 months in a metabolic rehabilitation unit. A multidisciplinary approach was used (combination of diet, physical exercise and psychotherapy)

Inclusion Criteria:

• age >= 18
• BMI >= 30
• one or more comorbidities (type 2 diabetes mellitus, dyslipidemia, high blood pressure, hyperuricemia, and others)

Exclusion Criteria:

• active cancer
• severe cognitive or functional impairments
• severe behavioral disorders
• known kidney failure (previous glomerular filtration rate <30 ml/min)
• known liver failure (Child B or C)