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The aim of this study is to evaluate the Desensitizing efficacy of polymeric nano calcium fluoride containing varnish and its implementation into clinical practice.
Increasing the demand to find a desensitizing agent that should be biocompatible, easy to apply, painless, not changing the dental color, fast onset, and maintain a long-term effect gives a highlight to the patented formula of the polymeric nano calcium fluoride which newly introduced into the practice .
OliNano SEAL is an innovative "varnish-like" protector based on a patented silicone polymer with a true nano technology that provides an exceptional adhesion to enamel and dentin without prior etching for approximately 12 months (other available products max. 2-3 months).
It consists of four components Silicone polymer provides excellent adhesion to enamel and dentine, with transparent formula. NANO-fluoroapatite flows into enamel micro cracks & seals it, penetrating into the dentinal tubules closing them eventually. As for the NANO-calcium fluoride it behaves as a fluoride reservoir, provides gradual and long-term fluoride release. The fourth component Amine fluoride (Olaflur) provides immediate fluoride ion release and accelerates natural remineralization.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| polymeric nano calcium fluoride containing varnish, NANO SEAL. | Experimental |
| |
| Casein Phosphopeptide Amorphous Calcium Phosphate Containing Fluoride Varnish,MI varnish | Other | CPP-ACP with 5%NaF |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| polymeric nano calcium fluoride containing varnish NANO SEAL | Combination Product | It consists of four components Silicone polymer provides excellent adhesion to enamel and dentine, with transparent formula. NANO-fluoroapatite flows into enamel micro cracks & seals it, penetrating into the dentinal tubules closing them eventually. As for the NANO-calcium fluoride it behaves as a fluoride reservoir, provides gradual and long-term fluoride release. The fourth component Amine fluoride (Olaflur) provides immediate fluoride ion release and accelerates natural remineralization. |
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analog Scale VAS | from 0-10 Pain absent: 0 Low pain:(1-3) Moderate pain: (4-6) Intense pain: (7-9) Extremely intense pain: 10. | six months |
| Schiff air score | from 0-3 0: Tooth/subject did not respond to the air stimulus.
| six months |
| Measure | Description | Time Frame |
|---|---|---|
| Dentinal tubule occlusion | Fully open, partially occluded and fully occluded dentinal tubules. (Percentage %) | six months |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D003807 | Dentin Sensitivity |
| ID | Term |
|---|---|
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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