| Primary | Self-report Ratings of Muscle Soreness | A muscle soreness inventory will be used to self-report the level of soreness. The muscle soreness inventory consists of rating soreness on a visual analog scale (VAS). A 10cm line is drawn with 0 (no soreness) on the left pole and 10 (extreme soreness) on the right pole. | | Posted | | Mean | Standard Deviation | score on a scale | | Baseline (Day 1) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Primary | Self-report Ratings of Muscle Soreness | A muscle soreness inventory will be used to self-report the level of soreness. The muscle soreness inventory consists of rating soreness on a visual analog scale (VAS). A 10cm line is drawn with 0 (no soreness) on the left pole and 10 (extreme soreness) on the right pole. | | Posted | | Mean | Standard Deviation | score on a scale | | Pre-exercise (Day 10) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Primary | Self-report Ratings of Muscle Soreness | A muscle soreness inventory will be used to self-report the level of soreness. The muscle soreness inventory consists of rating soreness on a visual analog scale (VAS). A 100mm line is drawn with 0 (no soreness) on the left pole and 100 (extreme soreness) on the right pole. | | Posted | | Mean | Standard Deviation | score on a scale | | Post-exercise (Day 12) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Primary | Self-report Ratings of Disability | Disability will be measured using the Lower Extremity Functional Scale (LEFS). LEFS score = SUM (points for all 20 activities) Interpretation: Minimum score: 0 Maximum score: 80 The lower the score the greater the disability. | | Posted | | Mean | Standard Deviation | score on a scale | | Baseline (Day 1) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Primary | Self-report Ratings of Disability | Disability will be measured using the Lower Extremity Functional Scale (LEFS). LEFS score = SUM (points for all 20 activities) Interpretation: Minimum score: 0 Maximum score: 80 The lower the score the greater the disability. | | Posted | | Mean | Standard Deviation | score on a scale | | Pre-exercise (Day 10) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Primary | Self-report Ratings of Disability | Disability will be measured using the Lower Extremity Functional Scale (LEFS). LEFS score = SUM (points for all 20 activities) Interpretation: Minimum score: 0 Maximum score: 80 The lower the score the greater the disability. | | Posted | | Mean | Standard Deviation | score on a scale | | Post-exercise (Day 12) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Secondary | Pain Anxiety Symptom Scale - 20 (PASS-20) | 20 item, 5-point rating scale that assesses 4 theoretically distinct components of pain-related anxiety including cognitive anxiety (items 1 to 5), fear of pain (items 6 to 10), escape/avoidance behavior (items 11 to 15), and physiological anxiety (items 16 to 20). Each subscale is worth 20 points. Subscales are combined to compute total score. The total scale ranges from 0 to 100; higher scores indicate worse outcome. | | Posted | | Mean | Standard Deviation | score on a scale | | Pre-exercise (Day 10) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Secondary | Pain Anxiety Symptom Scale (PASS-20) | 20 item, 5-point rating scale that assesses 4 theoretically distinct components of pain-related anxiety including cognitive anxiety (items 1 to 5), fear of pain (items 6 to 10), escape/avoidance behavior (items 11 to 15), and physiological anxiety (items 16 to 20). Each subscale is worth 20 points. Subscales are combined to compute total score. The total scale ranges from 0 to 100; higher scores indicate worse outcome. | | Posted | | Mean | Standard Deviation | score on a scale | | Post-exercise (Day 15) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Secondary | Pain Catastrophizing Scale (PCS) | 13-item, 5-point rating scale used to assess different thoughts that may be associated with experiencing pain. The PCS total score is computed by summing responses to all 13 items. PCS total scores range from 0 - 52. The PCS subscales are computed by summing the responses to the following items: Rumination: Sum of items 8, 9, 10, 11; Magnification: Sum of items 6, 7, 13; and Helplessness: Sum of items 1, 2, 3, 4, 5, 12; higher scores indicate worse outcome. | | Posted | | Mean | Standard Deviation | score on a scale | | Baseline (Day 1) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Secondary | Pain Catastrophizing Scale (PCS) | 13-item, 5-point rating scale used to assess different thoughts that may be associated with experiencing pain. The PCS total score is computed by summing responses to all 13 items. PCS total scores range from 0 - 52. The PCS subscales are computed by summing the responses to the following items: Rumination: Sum of items 8, 9, 10, 11; Magnification: Sum of items 6, 7, 13; and Helplessness: Sum of items 1, 2, 3, 4, 5, 12; higher scores indicate worse outcome. | | Posted | | Mean | Standard Deviation | score on a scale | | Pre-exercise (Day 10) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Secondary | Pain Catastrophizing Scale (PCS) | 13-item, 5-point rating scale used to assess different thoughts that may be associated with experiencing pain. The PCS total score is computed by summing responses to all 13 items. PCS total scores range from 0 - 52. The PCS subscales are computed by summing the responses to the following items: Rumination: Sum of items 8, 9, 10, 11; Magnification: Sum of items 6, 7, 13; and Helplessness: Sum of items 1, 2, 3, 4, 5, 12; higher scores indicate worse outcome. | | Posted | | Mean | Standard Deviation | score on a scale | | Post-exercise (Day 15) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Secondary | Fear of Pain Questionnaire (FPQ-9) | 9-item, 5-point rating scale to quantify fear of specific situations that normally produce pain. Each subscale contains 3 items, so the possible range of scores for each subscale is 3 through 15. Subscales are combined to compute total score. The Total score has a range of 9 through 45; higher scores indicate worse outcome. | | Posted | | Mean | Standard Deviation | score on a scale | | Baseline (Day 1) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Secondary | Fear of Pain Questionnaire (FPQ-9) | 9-item, 5-point rating scale to quantify fear of specific situations that normally produce pain. Each subscale contains 3 items, so the possible range of scores for each subscale is 3 through 15. Subscales are combined to compute total score. The Total score has a range of 9 through 45; higher scores indicate worse outcome. | | Posted | | Mean | Standard Deviation | score on a scale | | Pre-exercise (Day 10) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Secondary | Maximal Voluntary Isometric Contraction (MVIC) | maximum voluntary force produced during a static muscle contraction | | Posted | | Mean | Standard Deviation | Newton-meters | | Pre-exercise (Day 10) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Secondary | Maximal Voluntary Isometric Contraction (MVIC) | maximum voluntary force produced during a static muscle contraction measured in Newton-meters. | | Posted | | Mean | Standard Deviation | force output in Newton-meters | | Post-exercise (Day 12) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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| Secondary | Maximal Voluntary Isometric Contraction (MVIC) | maximum voluntary force produced during a static muscle contraction measured as Newton-meters. | | Posted | | Mean | Standard Deviation | force output in Newton-meters | | Post-exercise (Day 15) | | | | ID | Title | Description |
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| OG000 | Active CBD-extract | Active Dose (2000mg/30mL hemp extract = 67.5mg/day) Active CBD: Participants will be provided a viscous liquid in a bottle with a syringe dropper containing CBD-extract oil at concentrations of 2000mg/30mL (high). | | OG001 | Vehicle-Control (Placebo) | (0mg/30mL hemp extract = no hemp extract) Vehicle Control (Placebo): Participants will be provided a viscous liquid in a bottle with a syringe dropper containing placebo containing no CBD oil (0mg/30 mL). |
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