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In this study, we compared a negative pressure wound therapy, versus a conventional dressing in order to evaluate the most efficient wound therapy closure after axillary and inguinal lymph nodes dissections in the management of metastatic skin tumors. A vacuum assisted closure therapy should prevent these comorbidities.
Lymphorrhoea, lymphedema and lymphocyte are significant and common complications after axillary and inguinal lymph nodes dissections. A vacuum assisted closure therapy should prevent these comorbidities. In this study, we compared PREVENA, a negative pressure wound therapy, versus conventional dressings. We evaluated the wound complications at the seventh day, the thirtieth day and at this end of the first year after surgery. It is a retrospective study of about ninety lymph nodes dissections among with there were seventy times the use of a negative pressure wound therapy, PREVENA.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PREVENA | A vacuum wound closure therapy like PREVENA is applied after axillary or inguinal lymph node dissection in the management of metastatic skin tumors |
| |
| NON PREVENA | A conventional wound closure is applied after axillary or inguinal lymph node dissection in the management of metastatic skin tumors |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PREVENA | Device | A negative pressure wound closure therapy is used after lymph node dissection |
|
| Measure | Description | Time Frame |
|---|---|---|
| Is there a visible scar disunion ? | Yes if there is a scar opening, no if there isn't | between day 1 and day 7, between day 7 and day 30, between day 30 and first year end |
| Is there lymphorrhoea from the scar ? | Yes if there is lymph coming from the the scar, no if there isn't. | between day 1 and day 7, between day 7 and day 30, between day 30 and first year end |
| Measure | Description | Time Frame |
|---|---|---|
| Are there lymphocele punctures ? | Yes if there is any lymphocele puncture, no if there isn't | between day 1 and day 7, between day 7 and day 30, between day 30 and first year end |
| Is there any lymphoedema ? |
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Inclusion Criteria:
Exclusion Criteria:
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major patient affected by a metastatic skin tumors
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| Name | Affiliation | Role |
|---|---|---|
| Manuela PEREZ | Visceral Surgery Department | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHRU | Nancy | 54000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36283927 | Derived | Poirier A, Albuisson E, Bihain F, Granel-Brocard F, Perez M. Does Preventive Negative Pressure Wound Therapy (NPWT) reduce local complications following Lymph Node Dissection (LND) in the management of metastatic skin tumors? J Plast Reconstr Aesthet Surg. 2022 Dec;75(12):4403-4409. doi: 10.1016/j.bjps.2022.08.054. Epub 2022 Aug 24. |
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Yes if there is arm or leg lymphoedema, no if there isn't
| between day 1 and day 7, between day 7 and day 30, between day 30 and first year end |
| ID | Term |
|---|---|
| D008545 | Melanoma |
| D012878 | Skin Neoplasms |
| D002294 | Carcinoma, Squamous Cell |
| D018278 | Carcinoma, Neuroendocrine |
| D008207 | Lymphatic Metastasis |
| ID | Term |
|---|---|
| D018358 | Neuroendocrine Tumors |
| D017599 | Neuroectodermal Tumors |
| D009373 | Neoplasms, Germ Cell and Embryonal |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D009380 | Neoplasms, Nerve Tissue |
| D018326 | Nevi and Melanomas |
| D009371 | Neoplasms by Site |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D018307 | Neoplasms, Squamous Cell |
| D000230 | Adenocarcinoma |
| D009362 | Neoplasm Metastasis |
| D009385 | Neoplastic Processes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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