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The investigators studied the influence of two aproved rehabilitative treatments, connective tissue techniques and lymphatic drainage, on acute inflammation markers. Furthermore, the role of mediterranean diet on the same values was investigated in the first postoperative period
The main objective of this study is to demonstrate the effectiveness of lymphatic drainage and connective tissue techniques in modulating systemic inflammation. Another objective is to evaluate the existence, at baseline, of a correlation between the inflammation indices and the level of adherence to the Mediterranean diet.
Methods. 34 patients were recruited, and divided into three groups. The control group followed the normal rehabilitation protocol. The other two groups were subjected, in addition to the standard treatment, to manual lymphatic drainage treatment or connective tissue techniques. The outcomes (PCR, ESR, Oedema) were recorded in three stages: upon entering the hospital, 1 week after entry and at follow-up 21 days after surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lymphatic drainage | Experimental | Patients subjected to manual lymphatic drainage |
|
| Connective tissue | Experimental | Patients subjected to connective tissue massage |
|
| control group | Active Comparator | Subjects hat followed standard rehabilitative treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lymphatic drainage | Procedure | The interventions follow the validated techniques normally used in international rehabilitation |
|
| Measure | Description | Time Frame |
|---|---|---|
| CRP variation | blood test | 21 days |
| ESR variation | blood test | 21 days |
| lower limb oedema | leg circumference | 21 days |
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Inclusion criteria
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| Name | Affiliation | Role |
|---|---|---|
| Sergio Rigoni | Presidio Ospedaliero di Asiago | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| presidio ospedaliero di Asiago | Asiago | Vicenza | 36012 | Italy | ||
| ULSS 7 Pedemontana |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34099953 | Derived | Rigoni S, Tagliaro L, Bau D, Scapin M. Effectiveness of two rehabilitation treatments in the modulation of inflammation during the acute phase in patients with knee prostheses and assessment of the role of the diet in determining post-surgical inflammation. J Orthop. 2021 May 15;25:237-243. doi: 10.1016/j.jor.2021.05.016. eCollection 2021 May-Jun. |
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| ID | Term |
|---|---|
| D000073297 | Manual Lymphatic Drainage |
| ID | Term |
|---|---|
| D008405 | Massage |
| D064746 | Therapy, Soft Tissue |
| D026201 | Musculoskeletal Manipulations |
| D000529 | Complementary Therapies |
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Randomized Controlled Trial
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|
| Asiago |
| Vicenza |
| 36012 |
| Italy |
| D013812 |
| Therapeutics |
| D004322 | Drainage |
| D026741 | Physical Therapy Modalities |
| D012046 | Rehabilitation |