Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 2019-A03026-51 | Other Identifier | ID RCB |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The main objective of this project is to identify behavioral specificities of the proactive emotional brain among bipolar patients, compared to healthy subjects. These could contribute to some of the emotional processing biases that can be observed in these patients. To achieve this goal, two behavioral tasks will be administer (emotional stroop and emotional stimuli categorization task) to bipolar patients and control subjects, and their performances will be compared.
This is a case-control non-interventional study comparing bipolar patients to matched healthy controls during one assessment visit at the University Hospital of Grenoble.
The experimentation phase takes place in three stages: first, the experimenter collects demographic data (age and level of study, lack of medical history and treatments that may interfere with the task). For bipolar subjects, it also collects the type of bipolarity, the type and date of the last episode, the age of the onset of the disease and the treatment.
Secondly, the subject performs a classic Stroop task lasting 3 to 5 minutes, including instructions.
Finally, the subject performs the two main tasks: the emotional Stroop task lasting about 20 minutes and then the task of emotional stimuli categorization lasting about 15 minutes.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bipolar patients | Bipolar patients (type I,II, NOS) of the bipolar disorder expert center of CHU Grenoble Alpes. |
| |
| Healthy controls | Volunteers without any psychiatric disease matching inclusion criteria |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Emotional Stroop Task | Behavioral | Classic Stroop task The subject names one of the 3 colors of the crosses on a sheet.Then, the subject must read the words written on the sheet for 45 seconds.These are the words: RED, BLUE and GREEN, written in black color. The subject must name the color of the word. Emotional Stroop task This is a computed task in which the patient is asked to answer both as accurately and as quickly as possible. The target stimulus is an emotional face of joy or anger, surmounted by the word "joy" or "anger".The subject must respond using the arrow corresponding to the face he sees. A training phase is offered to the subject. 3 / Categorization task For each trial the participant will visualize a short emotional film or not. Then, the participant will have to choose, the emotion corresponding to what he just saw. A training period is offered too. |
| Measure | Description | Time Frame |
|---|---|---|
| performances at the emotional Stroop task | percentage of correct answers ( in %), reaction time ( in seconds) and inverse efficiency score ( N.A) | day1 |
| Measure | Description | Time Frame |
|---|---|---|
| sensitivity to interference during Stroop tasks | -reaction time (in seconds) in the different conditions of the task (reading in the congruent condition, interference during the incongruent condition) | day1 |
| Effect of mood state (depressive state) on behavioral tasks' performances |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
bipolar patients cohort followed-up in the Expert Center of University Hospital of Grenoble
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Mircea Polosan, MD, PhD | University Hospital, Grenoble | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Grenoble Alpes | La Tronche | Isère | 38 700 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26024463 | Background | Beffara B, Wicker B, Vermeulen N, Ouellet M, Bret A, Molina MJ, Mermillod M. Reduction of interference effect by low spatial frequency information priming in an emotional Stroop task. J Vis. 2015;15(6):16. doi: 10.1167/15.6.16. | |
| Background | Golden, C. (1978). Diagnosis and Rehabilitation in Clinical Neuropsychology. College of Psychology: Faculty Books and Book Chapters. https://nsuworks.nova.edu/cps_facbooks/48 |
Not provided
Not provided
If the patient accepts all the characteristics useful for the study will be available in our results.
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D001714 | Bipolar Disorder |
| ID | Term |
|---|---|
| D000068105 | Bipolar and Related Disorders |
| D019964 | Mood Disorders |
| D001523 | Mental Disorders |
Not provided
Not provided
Not provided
Not provided
Not provided
|
|
assessment of the impact of mood scales (MADRS) scores on behavioral tasks performances |
| day 1 |
| Effect of mood state (hypo/manic state) on behavioral tasks' performances | assessment of the impact of mood scales (YMRS) scores on behavioral tasks performances | day 1 |